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Fig. 7 | BMC Medicine

Fig. 7

From: Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

Fig. 7

SF upregulates MMP13 expression in hucMSCs via a MAPK-AP1 pathway. A Protein bands and quantitation of their expression in hucMSCs treated with SF. B hucMSCs treated with SF and p38 inhibitor. C hucMSCs treated with SF and Erk1/2 inhibitor. D hucMSCs treated with SF and JNK inhibitor. E hucMSCs nuclei treated with SF and p38 inhibitor. F hucMSCs nuclei treated with SF and Erk1/2 inhibitor. G hucMSCs nuclei treated with SF and JNK inhibitor. Values are presented as mean ± SD. #P < 0.05 and ##P < 0.01 versus NC group; *P < 0.05 and **P < 0.01 versus SF group. All experiments were repeated at least three times

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