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Fig. 1 | BMC Medicine

Fig. 1

From: Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function

Fig. 1

Deletion of genomic sequences spanning rs71052682 resulted in the downregulation of NISCH expression in U251 and U87-MG cells. A DNA fragment containing rs71052682 was knocked out using the CRISPR-Cas9 system. B Relative mRNA expression of NISCH in U251 and U87-MG cells. Data are shown as mean ± SD, and Student’s t-test was used to perform the significance test. *P < 0.05

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BMC Medicine

ISSN: 1741-7015

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