Fig. 3

Dysfunction-associated genetic profiles in the progressive stages. A Overlap between the progressive dysfunction-associated genes and the schizophrenia-related genes from the AHBA in situ hybridization data. A duration range was recognized for each stage. Thirty-eight related genes were identified across all stages. Each stage is linked with distinct genes (presented in different colors). Unrelated genes are shown in gray. B Positive correlations (with the most significant correlations) between associated gene expression and case–control t-maps. C Negative correlations (with the most significant correlations) between associated gene expression and case–control t-maps