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Table 2 The incidence case, follow-up person-years and rate of individual hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, coronary artery disease and heart failure comorbidities

From: Investigating the risk of metabolic and cardiovascular comorbidities among patients with parathyroid cancer: a nationwide representative cohort study in Taiwan

 

Hypertension

Diabetes

Hyperlipidemia

 

Control

PTC

Log-rank

Control

PTC

Log-rank

Control

PTC

Log-rank

N

206

45

 

262

58

 

330

68

 

 Event

23

6

 

3

6

 

7

6

 

 Person-year

1113

207

 

1499

284.3

 

1832

323.2

 

 Incidence rate (/1000 person-year)

20.7

29

0.44

2

21.1

 < 0.001

3.8

18.6

0.002

 Unadjusted

1

1.43 (0.58–3.51)

 

1

10.07 (2.51–40.41)

 

1

4.78 (1.6–14.27)

 

 Model 1

1

1.52 (0.48–4.84)

 

1

15.18 (2.48–92.98)

 

1

8.35 (2.1–33.25)

 

 Model 2

1

1.5 (0.6–3.73)

 

1

10.55 (2.59–43.02)

 

1

4.7 (1.57–14.07)

 

 Model 3

1

1.12 (0.37–3.41)

 

1

9.28 (1.72–50.07)

 

1

5.86 (1.61–21.31)

 
 

Atrial fibrillation

Coronary artery disease

Heart failure

 

Control

PTC

Log-rank

Control

PTC

Log-rank

Control

PTC

Log-rank

N

344

70

 

335

69

 

307

64

 

 Event

6

4

 

10

8

 

7

6

 

 Person-year

1919

325.1

 

1868

333.8

 

1716

307.7

 

 Incidence rate (/1000 person-year)

3.1

12.3

0.034

5.4

24

 < 0.001

4.1

19.5

0.002

 Unadjusted

1

3.6 (1.01–12.78)

 

1

4.51 (1.78–11.46)

 

1

4.98 (1.66–14.92)

 

 Model 1

1

3.81 (1.06–13.73)

 

1

4.44 (1.73–11.42)

 

1

4.89 (1.6–14.97)

 

 Model 2

1

3.38 (0.95–12.05)

 

1

4.74 (1.86–12.13)

 

1

5.28 (1.71–16.33)

 

 Model 3

1

2.09 (0.46–9.59)

 

1

1.69 (0.5–5.63)

 

1

4.46 (1.18–16.84)

 
  1. Model 1: adjusted for age and sex; Model 2: adjusted occupation, urbanization, average month income; Model 3: Model 2 additionally chronic kidney disease, nephrolithiasis, osteoporosis
  2. PTC parathyroid cancer