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Fig. 3 | BMC Medicine

Fig. 3

From: CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

Fig. 3

CUS and CSF1Ri enhanced anxiety in mice. (A) Schema representing experimental design. (B) ratio (%) of travel distance in corners (m) against total travel distance (m) in an open field and (C) ratio (%) of time spent in open arms against closed arms in an elevated plus maze (n = 9–10 mice per group). Ctr: Control; CUS: chronic unpredictable stress; CSF1Ri: CSF1R inhibitor; EPM: elevated plus maze; OFT: open field test; Veh: Vehicle. Data presented as mean ± SEM; */**/***/**** p < 0.05/0.01/0.001/0.0001 compared to Ctr-Veh. Two-way ANOVA with Bonferroni’s correction

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BMC Medicine

ISSN: 1741-7015

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