CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

Table 1 Demographic characteristics of FES patients and HCs

Demographics	FES (n = 51)	HC (n = 46)	F or χ2	P
Sex (M/F)	18/33	23/23	2.143	0.143
Age (years)^a	30.59 (1.18)	34.00 (1.46)	1388.000	0.120
Education (years)^a	12.75 (0.49)	13.28 (0.33)	1298.500	0.354
CTQsum^a	81.55 (5.49)	70.02 (4.78)	727.500	0.125
PSSsum^a	23.14 (0.99)	21.39 (0.67)	893.000	0.043
Age of illness onset (years)	29.27 (1.17)
Illness duration (months)	11.70 (2.09)
PANSSt	75.69 (2.03)
White blood cells (10⁶/ml)^a	7.60 (1.08)	6.01 (0.25)	856.000	0.085
Plasma CSF1R (ng/ml)	18.55 (1.03)	21.26 (0.766)	5.539	0.021

All data were reported as mean (SEM), FES first episode schizophrenia, HC healthy control, FDR false discovery rate, CSF1R colony stimulating factor 1 receptor; CTQ childhood trauma questionnaire; PSS perceived stress scale; PANSSt positive and negative symptom scale total score. CSF1R (ANCOVA controlled by age, sex, and white blood cells); Significant p values are shown in bold texts. ^aMann-Whitney U test

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