Fig. 4

Development and validation of the CLTRP score in breast cancer cohorts. A Screening workflow of 31 genes from Fig. 3C. B Univariate Cox analysis of 18 candidate genes associated with prognosis. C Forest plot of univariate Cox analysis for clinicopathological factors and the CLTRP score. D Forest plot of multivariate Cox analysis of the factors significant in the univariate Cox analysis (p < 0.05). E, F Kaplan–Meier survival curve of overall survival between the high and low CLTRP score groups in the TCGA cohort and METABRIC cohort