Transcriptional level of inflammation markers associates with short-term brain structural changes in first-episode schizophrenia

Table 1 Demographic and clinical profile of 38 first-episode patients with schizophrenia and 51 healthy controls

	Controls	Patients	Between-group comparisons (p, t or χ²)^a
Age (years)	21.14 ± 4.03	23.03 ± 6.46	0.09	t = − 1.69
Sex (male/female)	33/18	21/17	0.37	χ² = 0.81
Education (years)	13.89 ± 2.65	12.26 ± 2.97	0.01	t = 2.72
Follow-up interval (days)	148.29 ± 56.20	131.51 ± 4.46	0.04	t = 2.13
Illness duration (years)^b	/	0.46 (0.17, 1)		/
Stay in hospital (days)	/	18.45 ± 8.25		/
Antipsychotics (olanzapine equivalent, mg/day)^b,c	/	9.84 (6.78, 14.94)		/

^aGroup comparison was conducted using two-sample t-test. Nominal variables (sex) were compared with chi-square statistics
^bIllness duration and dose of antipsychotic medication did not follow a normal distribution; therefore, the median (25th, 75th percentile) values were reported
^cAntipsychotic dose was converted to a defined daily dose (https://doi.org/10.1093/schbul/sbv167)

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