Study characteristic | No. (%) of RCTs (N = 157) |
---|---|
Year of publication | |
 1995–2000 | 10 (6.4) |
 2001–2005 | 25 (15.9) |
 2006–2010 | 33 (21.0) |
 2011–2015 | 58 (36.9) |
 2016–2020 | 31 (19.7) |
Continent | |
 Europea | 69 (43.9) |
 Australia/New Zealand | 15 (9.6) |
 North America | 62 (39.5) |
 Asia | 9 (5.7) |
 South America | 1 (0.6) |
 Multi-continent | 1 (0.6) |
Site | |
 Multi-center | 129 (82.2) |
 Single center | 24 (15.3) |
 Not reported | 4 (2.5) |
Number of arms | |
 Two arms | 145 (92.4) |
 Three arms | 11 (7) |
 Four arms | 1 (0.6) |
Settingsb | |
 Clinic | 61 (38.9) |
 Home | 59 (37.6) |
 Hospital | 5 (3.2) |
 Community | 5 (3.2) |
 Long-term care | 1 (0.6) |
 Not reportedc | 70 (44.6) |
 Not applicabled | 37 (23.6) |
Sample size (no. of patients) | |
 40–200 | 50 (31.8) |
 201–500 | 49 (31.2) |
 501–1000 | 16 (10.2) |
 1001–2000 | 21 (13.4) |
  > 2000 | 19 (12.1) |
 Not involving patientse | 2 (1.3) |
Sample size (no. of caregivers) | |
 60–100 | 6 (3.8) |
 101–300 | 9 (5.7) |
  > 300 | 5 (3.2) |
 Not involving caregivers | 137 (87.3) |
Sample size (no. of providers) | |
 9–100 | 17 (10.8) |
 101–200 | 8 (5.1) |
 201–900 | 8 (5.1) |
 Not involving providers | 124 (79) |
Study duration with follow up | |
 12–19 months | 14 (8.9) |
 20–29 months | 23 (14.6) |
 30–39 months | 43 (27.4) |
 40–49 months | 25 (15.9) |
  > 50 months | 13 (8.3) |
 Not reported | 39 (24.8) |
Funding | |
 Government | 84 (53.5) |
 Mixedf | 36 (22.9) |
 Commercial | 8 (5.1) |
 Research organization | 8 (5.1) |
 Voluntary organization | 5 (3.2) |
 Charitable trust | 4 (2.5) |
 Not reported | 12 (7.6) |