Table 3 Lack of early improvement cut-offs (0–20%) as predictors of nonresponse to antipsychotics at endpoint
Evaluation time of early improvement | Cutoff value | Total accuracy (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|
Week 2 |  ≤ 0% | 68.0 | 12.8 | 98.7 | 84.8 | 67.1 |
 < 5% | 78.6 | 51.5 | 93.6 | 81.7 | 77.7 | |
 < 10% | 79.2 | 70.8 | 83.8 | 70.8 | 83.8 | |
 < 15% | 74.0 | 93.4 | 63.2 | 58.5 | 94.6 | |
 < 20% | 74.0 | 93.4 | 63.1 | 58.5 | 94.5 | |
Week 4 |  ≤ 0% | 64.5 | 0.7 | 100.0 | 100.0 | 64.4 |
 < 5% | 67.7 | 8.9 | 100.0 | 100.0 | 66.6 | |
 < 10% | 75.6 | 31.9 | 99.6 | 98.0 | 72.7 | |
 < 15% | 85.8 | 68.0 | 95.6 | 89.6 | 84.4 | |
 < 20% | 90.7 | 87.5 | 92.5 | 86.7 | 93.0 |