Fig. 1
From: A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth
Strategic approach for SNP prioritization and transcription factor prediction. Our procedure started with an LD expansion of the GWAS-identified index SNP from the discovery phase using criteria r2 > 0.8 using the PLINK software package (version 1.90b) with EU ancestry. The resulting set of 49 SNPs was used for subsequent analysis to prioritize the causal SNP and to predict the differential binding of transcription factors. This analysis identified rs7889204 as the most likely causal SNP