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Fig. 5 | BMC Medicine

Fig. 5

From: A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

Fig. 5

The risk “C” allele of rs7889204 shows decreased reporter activity. A 4.3-kb region surrounding rs7889204 with either the reference (T) or non-reference (C) SNP haplotypes were inserted in front of a 1 kb sequence including the first 816 bases before the transcription start site of AGTR2 in a pNL1.1 nanoluciferase reporter construct. Nanoluciferase readings were normalized to the constitutive control for each replicate. Each bar represents the mean across three experimental replicates and the standard deviation

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