Fig. 2

Causal associations between IDPs and stroke in the forward MR and reverse MR. The heatmap plot shows the causal associations between IDPs with at least one significant MR signals in forward and reverse MR and stroke. The pattern diagram in the bottom shows the brain anatomical region of corresponding IDPs. AS, any stroke; AIS, any ischemic stroke; CES, cardioembolic stroke; FA, fractional anisotropy; ISOVF, isotropic volume fraction; MD, mean diffusivity; SVS, small vessel stroke