Fig. 3
Tmigd1INT-KO mice are predisposed to chemically induced acute colitis. A, B Body weight and Disease Activity Index (DAI) score; WT+water (n=8), Tmigd1INT-KO+water (n=8), WT+DSS (n=10), Tmigd1INT-KO+DSS (n=12). C Representative images of mouse colons. D Colon length; WT+water (n=8), Tmigd1INT-KO+water (n=8), WT+DSS (n=10), Tmigd1INT-KO+DSS (n=12). E Representative colonic histopathological images. Scale bars, 200 μm. F Histological scores; WT+water (n=8), Tmigd1INT-KO+water (n=8), WT+DSS (n=10), Tmigd1INT-KO+DSS (n=12). G Representative colonoscopy images. H Endoscopic scores. Every group, n=3. I, J Body weight and colon length; WT+Alcohol (n=10), Tmigd1INT-KO+Alcohol (n=10), WT+TNBS (n=10), Tmigd1INT-KO+TNBS (n=15). K Representative images of mouse colons. L Representative colonic histopathological images. Scale bars, 200 μm. M Histological scores; WT+Alcohol (n=10), Tmigd1INT-KO+Alcohol (n=10), WT+TNBS (n=10), Tmigd1INT-KO+TNBS (n=15). Data are expressed as mean ± SEM. ns, no significance, * p<0.05, ** p<0.01, *** p<0.001