Fig. 3
Comparison of ICERs for Vaccine Characteristic and Coverage Scenarios compared to the Status Quo no-new-vaccine baseline for each vaccine product. The Basecase M72/AS01E scenario assumes a 50% efficacy POD vaccine efficacious with any infection status at the time of vaccination, with 10 years’ duration of protection reaching 80% coverage for 15-year-olds and 70% coverage for those aged 16–34. Each M72/AS01E scenario is delivered routinely to those aged 15 and as a campaign for those aged 16–34. The Basecase BCG-revaccination scenario assumes a 45% efficacy POI vaccine efficacious with no current infection at the time of vaccination, with 10 years duration of protection and reaching 80% coverage. Each BCG-revaccination scenario is delivered routinely to those aged 10 and as a campaign for those aged 11–18. The scenarios on the figure are labelled with the difference in product characteristics for that scenario compared to the Basecase. The 20 years’ protection and 60% efficacy scenarios for M72/AS01E overlap and appear as one point on the figure