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Table 3 Risk of hip fracture in occasional meat-eaters, pescatarians, and vegetarians compared to regular meat-eaters in UK Biobank participants, stratified by age, sex, and body mass index

From: Risk of hip fracture in meat-eaters, pescatarians, and vegetarians: a prospective cohort study of 413,914 UK Biobank participants

Stratifying variable

n cases, adjusted HR (95% CI)

p interaction

Age

 

 < 60 years

 

 ≥ 60 years

 

 Regular meat-eaters (reference)

514/152,486

1.00

1531/106,279

1.00

 

 Occasional meat-eaters

317/75,670

1.03 (0.89, 1.18)

993/62,284

0.98 (0.91, 1.07)

 

 Pescatarians

31/6747

1.15 (0.80, 1.65)

47/2810

1.04 (0.77, 1.39)

 

 Vegetarians

32/5770

1.58 (1.10, 2.26)

38/1868

1.45 (1.04, 2.00)

0.9

Sex

 

Male

 

Female

 

 Regular meat-eaters (reference)

883/139,354

1.00

1162/199,411

1.00

 

 Occasional meat-eaters

381/54,842

0.98 (0.87, 1.10)

929/83,112

1.00 (0.92, 1.09)

 

 Pescatarians

19/2811

1.29 (0.82, 2.03)

59/6746

1.02 (0.79, 1.33)

 

 Vegetarians

24/2681

2.04 (1.36, 3.08)

46/4957

1.32 (0.98, 1.78)

0.3

BMI

 

BMI ≤ 22.5

 

BMI > 22.5

 

 Regular meat-eaters (reference)

343/25,794

1.00

1702/232,971

1.00

 

 Occasional meat-eaters

279/21,297

0.86 (0.74, 1.01)

1031/116,657

1.06 (0.98, 1.15)

 

 Pescatarians

27/2564

0.90 (0.61, 1.33)

51/6993

1.22 (0.92, 1.61)

 

 Vegetarians

31/1925

1.61 (1.12, 2.34)

39/5713

1.42 (1.03, 1.96)

0.08

  1. All models controlled for age and were adjusted for the following (all at recruitment): region (England, Scotland, Wales), sex (male, female), ethnicity (white, black, Asian, mixed, other), Townsend deprivation index (continuous), live alone (yes, no), smoking (current, former, never), supplementation (yes, no), physical activity in MET-minutes per week (continuous), alcohol consumption in drinks per day (continuous), body mass index (continuous), number of children (0, 1, 2, ≥ 3), menopausal status (premenopausal, postmenopausal), hormone replacement therapy (current, former, never), diabetes (yes, no), cancer (yes, no), cardiovascular disease (yes, no), and other fracture (yes, no). Each potential effect modifier was omitted from their adjustment set
  2. HR (95% CI) hazard ratio (95% confidence interval), BMI body mass index