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Table 1 Individual characteristics

From: Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study

 

Controls

GP-based depression cases

TRD cases

Group comparison

N

173,786

18,330

2199

 

Age

57.42 (±8.11)

56.11 (±7.95)

56.43 (±7.82)

224.6 (\(<\!\!10^{-10}\))

\(\%\) female

0.485

0.636

0.724

1804 (\(<\!\!10^{-10}\))

BMI

27.38 (±4.67)

28.26 (±5.37)

29.41 (±5.96)

359.1 (\(<\!\!10^{-10}\))

CRP (mg/L)

2.54 (±4.35)

2.99 (±4.57)

3.64 (±5.42)

109.7 (\(<\!\!10^{-10}\))

CIDI_MDDa

2 (±2.84)

5.45 (±2.19)

6.63 (±1.68)

3290 (\(<\!\!10^{-10}\))

PHQ9a

2.11 (±2.89)

4.52 (±5.09)

9.06 (±6.83)

2240 (\(<\!\!10^{-10}\))

  1. Mean (±SD)
  2. a CIDI and PHQ9 were measured in a different, partly overlapping subset of UKB participants (\(n=146,067\))
  3. Comparisons across groups are performed with analysis of variance (ANOVA) tests, and F-values and p-values are reported. A \(\chi ^2\) test was used to compare the proportion of females across the three groups