Table 4 Interaction analysis of social, physical, and psychological health of AYA survivors compared to the matched general population by race/ethnicity (N = 4932)

General health, poor/fair

1.59 (1.17–2.15)

1.30 (0.58–2.78)

1.35 (0.79–2.30)

2.93 (2.27–3.77)

 < 0.01

Social health

 Education, less than high school graduate

1.14 (0.81–1.58)

0.71 (0.25–1.73)

0.63 (0.38–1.03)

1.13 (0.80–1.59)

0.07

 Marital status, non-coupled

1.33 (1.04–1.71)

1.15 (0.58–2.37)

1.49 (0.91–2.44)

0.95 (0.73–1.22)

0.14

 Yearly household income, less than $20,000

1.09 (0.80–1.46)

0.97 (0.44–2.03)

1.29 (0.75–2.18)

1.02 (0.74–1.38)

0.82

 Current job status, unemployed

1.34 (1.03–1.73)

1.38 (0.69–2.75)

0.63 (0.37–1.06)

1.10 (0.87–1.38)

0.08

Physical health

 Health behavior

  Smoking status, former/current

1.62 (1.26–2.07)

1.79 (0.90–3.58)

0.89 (0.49–1.57)

0.92 (0.67–1.24)

 < 0.01

  Alcohol status, former/current

1.27 (0.73–2.26)

5.51 (1.34–37.53)

1.16 (0.54–2.50)

0.90 (0.63–1.31)

 < 0.01

 Reproductive health^b

  History of pregnant, yes

1.48 (0.94–2.44)

1.18 (0.29–7.99)

1.17 (0.42–4.13)

1.56 (0.97–2.62)

0.89

  History of birth, yes

1.48 (0.94–2.42)

0.76 (0.21–3.54)

1.15 (0.42–4.08)

1.73 (1.11–2.80)

0.60

 Comorbidities

  Cardiovascular

   Hypertension

1.34 (0.99–1.80)

1.78 (0.77–4.16)

1.32 (0.68–2.50)

0.79 (0.56–1.08)

0.04

   Stroke

1.55 (0.86–2.68)

3.21 (1.02–9.44)

2.53 (0.52–10.01)

1.26 (0.28–4.09)

 < 0.01

   Angina/angina pectoris

1.54 (0.80–2.78)

1.93 (0.27–9.36)

0.63 (0.03–3.97)

3.92 (1.27–11.54)

0.69

   Myocardial infarction

1.93 (1.11–3.26)

1.91 (0.27–9.36)

1.42 (0.21–6.05)

3.88 (0.75–18.02)

0.20

   Obesity

0.88 (0.68–1.14)

0.79 (0.40–1.57)

1.11 (0.68–1.82)

1.08 (0.84–1.38)

0.59

   Dyslipidemia

1.52 (0.99–1.80)

1.27 (0.77–4.16)

1.06 (0.68–2.50)

1.64 (0.56–1.08)

0.53

   DM

1.35 (0.87–2.06)

1.16 (0.41–2.96)

1.67 (0.81–3.27)

1.31 (0.85–1.98)

0.72

  Non-cardiovascular

   Arthritis

1.82 (1.39–2.38)

2.67 (1.26–5.72)

2.49 (1.35–4.56)

1.14 (0.75–1.70)

 < 0.01

   Thyroid disease

1.31 (0.93–1.83)

1.89 (0.69–4.71)

3.81 (2.06–6.97)

2.57 (1.73–3.76)

 < 0.01

   Asthma

1.63 (1.22–2.18)

0.79 (0.31–1.83)

2.65 (1.42–4.82)

1.92 (1.09–3.23)

 < 0.01

Psychological health

 Daily activity limitation due to emotional problem, yes

0.83 (0.29–2.42)

1.32 (0.04–32.88)

0.30 (0.06–1.41)

2.07 (0.77–5.61)

0.25

 Depression, PHQ-9 ≥ 10^c

2.63 (1.21–5.41)

1.03 (0.05–7.37)

0.73 (0.04–4.23)

2.34 (0.99–5.16)

0.23

 Suicide ideation, yes

2.01 (1.14–3.41)

1.16 (0.23–7.31)

1.34 (0.38–3.82)

1.47 (1.01–2.08)

0.92