Skip to main content

Table 4 Predefined hypotheses and results regarding construct validity of the TSC-PROM self and proxy version

From: Understanding the impact of tuberous sclerosis complex: development and validation of the TSC-PROM

Predefined hypotheses

Results

   
 

Self (n = 85)

 

Proxy (n = 78)

 

Moderately strong correlation between TSC-PROM physical functions domain and SF-36 physical component score

Moderately strong

r = 0.60; p < 0.001

Moderately strong

r = 0.55, p < 0.001

Moderately strong correlation between TSC-PROM mental functions domain and SF-36 mental component score

Strong

r = 0.83, p < 0.001

Moderately strong

r = 0.53, p < 0.001

Moderately strong correlation between TSC-PROM mental functions domain and total ASR or CBCL scores

Strong

r = 0.87, p < 0.001

Moderately strong

r = 0.61, p < 0.001

Weak to moderately strong correlations between TSC-PROM domain score and TSC-PROM HRQoL VAS score

Physical functions domain

Moderately strong

r = 0.59, p < 0.001

Weak

r = 0.44, p < 0.001

Mental functions domain

Moderately strong

r = 0.55, p < 0.001

Weak

r = 0.39, p < 0.001

Activities and participation domain

Moderately strong

r = 0.64, p < 0.001

Weak

r = 0.35, p = 0.003

Moderately strong correlations between TSC-PROM HRQoL VAS score and TSC-PROM VAS domain scores

Physical functions domain

Moderately strong

r = 0.67, p < 0.001

Moderately strong

r = 0.57, p < 0.001

Mental functions domain

Moderately strong

r = 0.65, p < 0.001

Moderately strong

r = 0.61, p < 0.001

Activities and participation domain

Moderately strong

r = 0.62, p < 0.001

Moderately strong

r = 0.59, p < 0.001

  1. Weak (r > 0.3), moderately strong (r > 0.5), and strong (r > 0.7) correlations