Skip to main content
Fig. 4 | BMC Medicine

Fig. 4

From: Identification and prediction model of placenta-brain axis genes associated with neurodevelopmental delay in moderate and late preterm children

Fig. 4

Association between DEGs and PBA-related genes from manual collection and validation of the PBA-related genes in placenta samples from CNBC study. a Venn plot of DEGs in MABC study with the PBA-related gene set. The significance of overlap was calculated by hypergeometric test. b Heatmap of log2FC for selected PBA-related genes. c–e Boxplot of FPKM for 14 PBA-related genes. c All; d male; e female. f In all placenta samples, CST3 mRNA expression are not significantly associated with MLPT. g In male placenta samples, GNB2, APOE, and CST3 mRNA expression are significantly increased in MLPTs. h In female placenta samples, CXCR2 and PTGS2 mRNA expression are significantly increased in MLPTs. *p < 0.05, **p < 0.01, Mann–Whitney-Wilcoxon test. Error bars indicate SEM

Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us