Table 2 66 CpG sites associated with T2D from two regression models (with and without BMI adjustment)
id | Gene | Cohort 1 | Cohort 2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
DF | Beta | p-value | DF | Beta | p-value | Model covariate | Is CpG significant in both models? | ||||
cg19693031 | TXNIP⊥ | 425 | 0.06 | 2.4E-21 | * | 362 | 0.04 | 7.6E-13 | * | no BMI | Both |
cg06291107 | BLCAP | 425 | -0.03 | 1.8E-16 | * | 362 | -0.02 | 3.7E-07 | no BMI | Both | |
cg10615580 | FLJ90757 | 425 | -0.04 | 3.8E-16 | * | 362 | -0.02 | 5.8E-06 | no BMI | Both | |
cg01676795 | POR⊥ | 425 | -0.06 | 7.6E-15 | * | 362 | -0.03 | 2.9E-06 | no BMI | Both | |
cg20567408 | PCID2 | 425 | -0.05 | 2.6E-14 | * | 362 | -0.02 | 3.6E-06 | no BMI | Both | |
cg13108341 | DNAH9 | 425 | -0.08 | 4.8E-14 | * | 362 | -0.05 | 1.2E-06 | no BMI | Both | |
cg19420720 | P4HB | 425 | -0.04 | 8.5E-14 | * | 362 | -0.02 | 4.7E-06 | no BMI | Both | |
cg00994936 | DAZAP1 | 425 | -0.03 | 2.3E-13 | * | 362 | -0.02 | 3.7E-06 | no BMI | Both | |
cg01219924 | FLJ90757 | 425 | -0.05 | 2.6E-12 | * | 362 | -0.03 | 7.7E-06 | no BMI | Both | |
cg11969813 | P4HB | 425 | -0.05 | 3.0E-12 | * | 362 | -0.03 | 1.9E-07 | no BMI | Both | |
cg27094813 | 425 | -0.04 | 5.1E-12 | * | 362 | -0.03 | 8.4E-09 | * | no BMI | Both | |
cg08088075 | 425 | -0.03 | 7.3E-12 | * | 362 | -0.03 | 3.9E-10 | * | no BMI | Both | |
cg19707375 | BAIAP2-AS1 | 425 | -0.04 | 2.1E-11 | * | 362 | -0.02 | 1.1E-06 | no BMI | Both | |
cg06721411 | DQX1⊥ | 425 | -0.04 | 3.9E-11 | * | 362 | -0.03 | 4.0E-08 | * | no BMI | Both |
cg22904406 | DAXX | 425 | -0.04 | 9.4E-11 | * | 362 | -0.02 | 1.0E-05 | no BMI | Both | |
cg12973487 | TCF3 | 425 | -0.03 | 1.1E-10 | * | 362 | -0.02 | 2.2E-06 | no BMI | Both | |
cg14334460 | NELF | 413 | -0.04 | 1.2E-10 | * | 361 | -0.02 | 3.0E-05 | with BMI | ||
cg00683922 | PFKFB2 | 425 | -0.04 | 1.2E-10 | * | 362 | -0.02 | 2.6E-06 | no BMI | Both | |
cg09879165 | CACNA2D2 | 425 | -0.02 | 2.0E-10 | * | 362 | -0.01 | 6.6E-07 | no BMI | Both | |
cg08992189 | HK1 | 425 | -0.04 | 6.2E-10 | * | 362 | -0.03 | 1.6E-07 | no BMI | Both | |
cg21124952 | 425 | -0.04 | 7.0E-10 | * | 362 | -0.02 | 3.4E-06 | no BMI | |||
cg12761421 | LGR6 | 413 | -0.03 | 1.6E-09 | * | 361 | -0.02 | 1.3E-05 | with BMI | ||
cg15007470 | TCF3 | 413 | -0.04 | 1.8E-09 | * | 361 | -0.02 | 1.5E-05 | with BMI | ||
cg27305772 | MUS81 | 413 | -0.03 | 2.3E-09 | * | 361 | -0.01 | 3.8E-05 | with BMI | ||
cg06646796 | DHRS2 | 425 | -0.03 | 2.4E-09 | * | 362 | -0.02 | 5.7E-06 | no BMI | ||
cg15326645 | 413 | -0.03 | 2.7E-09 | * | 361 | -0.02 | 6.6E-06 | with BMI | |||
cg19358608 | 425 | -0.03 | 3.4E-09 | * | 362 | -0.03 | 3.1E-06 | no BMI | |||
cg01689405 | SLC30A2 | 425 | -0.03 | 3.6E-09 | * | 362 | -0.02 | 4.7E-06 | no BMI | ||
cg21279706 | KIAA1257 | 425 | -0.04 | 5.6E-09 | * | 362 | -0.02 | 5.9E-06 | no BMI | ||
cg10167677 | THBS4 | 425 | -0.03 | 5.9E-09 | * | 362 | -0.03 | 2.0E-07 | no BMI | Both | |
cg12350057 | PPP1R3E | 413 | -0.05 | 6.0E-09 | * | 361 | -0.03 | 4.4E-05 | with BMI | ||
cg01307606 | 425 | -0.03 | 6.7E-09 | * | 362 | -0.02 | 1.5E-06 | no BMI | Both | ||
cg09777883 | 425 | -0.03 | 7.5E-09 | * | 362 | -0.03 | 2.3E-08 | * | no BMI | Both | |
cg09029192 | TNRC6C | 425 | -0.03 | 8.7E-09 | * | 362 | -0.02 | 1.0E-05 | no BMI | ||
cg20006294 | FRMD4B | 425 | -0.04 | 8.8E-09 | * | 362 | -0.02 | 4.2E-06 | no BMI | ||
cg03037271 | 425 | -0.03 | 1.1E-08 | * | 362 | -0.02 | 3.3E-07 | no BMI | |||
cg19225036 | PBRM1 | 413 | -0.04 | 1.1E-08 | * | 361 | -0.02 | 2.7E-05 | with BMI | ||
cg22896572 | 425 | -0.04 | 1.2E-08 | * | 362 | -0.04 | 1.0E-06 | no BMI | Both | ||
cg06555354 | SPRED2 | 413 | -0.04 | 1.2E-08 | * | 361 | -0.02 | 4.0E-05 | with BMI | ||
cg08110950 | 425 | -0.02 | 1.2E-08 | * | 362 | -0.02 | 8.4E-07 | no BMI | |||
cg18939666 | PEF1 | 425 | -0.03 | 1.3E-08 | * | 362 | -0.02 | 4.0E-07 | no BMI | ||
cg11692409 | SERPINF1 | 425 | -0.03 | 1.6E-08 | * | 362 | -0.02 | 4.7E-06 | no BMI | ||
cg17054691 | P4HB | 425 | -0.02 | 1.6E-08 | * | 362 | -0.02 | 8.7E-07 | no BMI | ||
cg13442656 | NR5A1 | 425 | -0.03 | 1.9E-08 | * | 362 | -0.02 | 1.2E-06 | no BMI | ||
cg00765623 | 425 | -0.03 | 1.9E-08 | * | 362 | -0.02 | 6.4E-06 | no BMI | |||
cg13547913 | OCIAD1 | 425 | -0.04 | 2.0E-08 | * | 362 | -0.03 | 8.5E-07 | no BMI | ||
cg26236214 | ARHGEF7 | 425 | -0.04 | 2.0E-08 | * | 362 | -0.03 | 2.4E-06 | no BMI | ||
cg27187909 | HDAC5 | 425 | -0.03 | 2.2E-08 | * | 362 | -0.02 | 5.0E-06 | no BMI | ||
cg22699725 | PFKFB2 | 413 | -0.03 | 2.4E-08 | * | 361 | -0.02 | 2.0E-05 | with BMI | ||
cg09627709 | LMTK2 | 425 | -0.04 | 3.7E-08 | * | 362 | -0.03 | 9.2E-06 | no BMI | ||
cg25693597 | P4HB | 413 | -0.03 | 4.4E-08 | * | 361 | -0.02 | 2.3E-05 | with BMI | ||
cg04406114 | POU2F2 | 413 | -0.03 | 4.6E-08 | * | 361 | -0.02 | 1.3E-05 | with BMI | ||
cg01280703 | TFF3 | 425 | -0.02 | 5.3E-08 | * | 362 | -0.02 | 4.7E-08 | * | no BMI | Both |
cg12067024 | S100A7A | 425 | -0.02 | 3.3E-06 | 362 | -0.02 | 1.4E-08 | * | no BMI | Both | |
cg26747273 | IDO2 | 413 | -0.05 | 6.1E-06 | 361 | -0.04 | 5.7E-08 | * | with BMI | ||
cg19629891 | LOC100288637 | 413 | -0.03 | 1.3E-05 | 361 | -0.03 | 4.8E-08 | * | with BMI | ||
cg01004980 | PRKAR2A | 425 | -0.03 | 2.0E-05 | 362 | -0.04 | 1.2E-09 | * | no BMI | ||
cg27182880 | LOC101929524 | 413 | -0.02 | 1.2E-04 | 361 | -0.02 | 3.0E-08 | * | with BMI | ||
cg02988288 | TXNIP;NBPF20;NBPF10 | 425 | 0.02 | 1.3E-04 | 362 | 0.02 | 3.9E-10 | * | no BMI | Both | |
cg04326337 | RPRD1B | 425 | -0.03 | 1.8E-04 | 362 | -0.04 | 2.4E-08 | * | no BMI | ||
cg00842231 | LOC55908;DOCK6 | 425 | -0.01 | 2.5E-04 | 362 | -0.01 | 3.8E-08 | * | no BMI | ||
cg00092123 | KIAA1211L | 425 | -0.01 | 2.8E-04 | 362 | -0.02 | 5.2E-08 | * | no BMI | ||
cg12331557 | DOCK10 | 413 | -0.02 | 4.1E-04 | 361 | -0.02 | 1.9E-08 | * | with BMI | ||
cg05919951 | HAUS8 | 413 | -0.02 | 4.2E-04 | 361 | -0.03 | 5.0E-08 | * | with BMI | ||
cg25358033 | TPCN1 | 425 | -0.01 | 4.2E-04 | 362 | -0.02 | 3.0E-08 | * | no BMI | ||
cg00929203 | 425 | -0.01 | 6.3E-04 | 362 | -0.02 | 2.7E-09 | * | no BMI | Both | ||