Table 2 Instrument strength of each trait of interest. N sample size, nSNPs number of SNPs at genome-wide significance (p < 5 x 10-8) after LD clumping
Trait | N | nSNPs | R2 | F statistic |
|---|---|---|---|---|
Age at menarche | 243,898 | 223 | 6.42 × 10−2 | 74.95 |
Age first had sexual intercourse | 219,486 | 53 | 9.44 × 10−3 | 39.46 |
Age at first live birth | 203,606 | 41 | 8.38 × 10−3 | 41.97 |
Age at last live birth | 203,356 | 9 | 1.92 × 10−3 | 43.46 |
Number of live births | 250,746 | 9 | 1.68 × 10−3 | 46.75 |
Ever parous status | 250,746 | 4 | 8.59 × 10−4 | 53.92 |
Age at menopause | 143,791 | 84 | 4.74 × 10−2 | 85.08 |
Lifetime number of sexual partners | 208,274 | 34 | 6.36 × 10−3 | 39.20 |
Childhood body size | 246,511 | 112 | 3.74 × 10−2 | 85.48 |
Adulthood body size | 246,511 | 160 | 3.23 × 10−2 | 51.39 |