Fig. 4

The expression levels of known placental dysfunction analytes across the SNF clusters. A Heatmaps showing the standardized mean expression levels of known placental dysfunction markers across the SNF clusters. In 27 of the 38 analytes presented, clusters II and III had the opposite extreme expression levels. B The same analysis in HDP, which includes placentas with any type of hypertension during pregnancy (severe PE and FGR + HDP groups). Again, clusters II and III had the opposite extreme expression levels. Analytes are ranked by their expression levels in cluster III. The color scale represents standardized expression levels. Red signifies higher levels; blue indicates lower levels. HDP, hypertensive disorders of pregnancy