Intervention | SOC group | CER-001 group | p-value |
---|---|---|---|
 | n = 5 | n = 15 |  |
Age (years), mean (SD) | 59 (10.29) | 56.6 (18.63) | 0.789 |
Male gender, n (%) | 2 (40%) | 4 (26.4%) | 0.573 |
Site of infection/sepsis, n(%) | |||
 Urine | 4 (80%) | 7 (46.7%) |  |
 Intra-abdominal | 0 | 6 (40%) | 0.238 |
 Other | 1 (20%) | 2 (13.3%) |  |
 Septic shock, n (%) | 1 (20%) | 6 (40%) | 0.795 |
Hospital unit, n(%) | |||
 Intensive care unit | 2 (40%) | 7 (46.7%) | 0.795 |
 Nephrology | 3 (60%) | 8 (53.3%) |  |
SOFA score, mean (SD) | 6.6 (6.07) | 6.07 (4.62) | 0.830 |
SAPS II score, mean (SD) | 31.8 (11.9) | 27.6 (14.2) | 0.569 |
Immunocompromised patients, n (%) | 1 (20%) | 1 (13.3%) | 0.717 |
Time for enrollment from hospital admission, median (IQR) | 0 (0–26) | 2 (1-6) | 1 |
Mean arterial pressure (MAP), mean (SD) | 85.8 (9.73) | 81 (14.22) | 0.495 |
Vasopressors use, n (%) | 1 (20%) | 6 (40%) | 0.573 |
Vasopressors dose (mcg/kg/min), mean (SD)a | 0.2 (0.1) | 0.17 (0.1) | 0.630 |
Mechanical ventilation, n(%) | 2 (40%) | 6 (40%) | 1 |
Acute kidney injury (AKI), n (%) | 3 (60%) | 8 (53.3%) | 0.795 |
Renal replacement therapy (RRT), n (%) | 1 (20%) | 2 (13.3%) | 0.717 |