Baseline assessment | 8-year follow-up assessment | Statistics | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
All (n = 814) | LCIBa (n = 555) | HCIBb (n = 259) | All (n = 814) | LCIBc (n = 555) | HCIBd (n = 259) | a vs b* | c vs d* | a vs c† | b vs d† | |
Age, years | ||||||||||
Index | 66.7 (4.82) | 66.3 (4.79) | 67.7 (4.76) | 74.8 (4.82) | 74.4 (4.79) | 75.7 (4.76) | 0.001 | 0.001 | < 0.001 | < 0.001 |
Spouse | - | - | - | 73.6 (6.01) | 73.4 (6.03) | 73.9 (5.98) | - | 0.24 | - | - |
p‡ | - | - | - | < 0.001 | 0.003 | < 0.001 | - | - | - | - |
Women | ||||||||||
Index | 331 (40.7) | 238 (42.9) | 93 (35.9) | 331 (40.7) | 238 (42.9) | 93 (35.9) | 0.06 | 0.06 | 1.00 | 1.00 |
Spouse | - | - | - | 483 (59.3) | 317 (57.1) | 166 (64.1) | - | 0.06 | - | - |
p‡ | - | - | - | < 0.001 | < 0.001 | < 0.001 | - | - | - | - |
Education, years | ||||||||||
Index | 10.3 (4.90) | 10.1 (4.90) | 10.8 (4.87) | 10.3 (4.90) | 10.1 (4.90) | 10.8 (4.87) | 0.04 | 0.04 | 1.00 | 1.00 |
Spouse | - | - | - | 10.0 (4.98) | 9.8 (5.03) | 10.5 (4.82) | - | 0.04 | - | - |
p‡ | - | - | - | 0.20 | 0.28 | 0.49 | - | - | - | - |
Exercise, MET*min/week | ||||||||||
Index | 2093 (3295) | 2244 (3556) | 1768 (2629) | 1437 (2092) | 1550 (2343) | 1195 (1382) | 0.03 | 0.007 | < 0.001 | < 0.001 |
Spouse | - | - | - | 1294 (1802) | 1395 (1966) | 1075 (1365) | - | 0.007 | - | - |
p‡ | - | - | - | 0.14 | 0.24 | 0.32 | - | - | - | - |
CIRS, points | ||||||||||
Index | 4.4 (2.85) | 2.9 (1.55) | 7.7 (2.10) | 6.7 (3.35) | 5.8 (2.95) | 8.9 (3.16) | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Spouse | - | - | - | 5.7 (3.15) | 5.5 (3.06) | 6.1 (3.31) | - | 0.02 | - | - |
p‡ | - | - | - | < 0.001 | 0.14 | < 0.001 | - | - | - | - |
High CIRS§ | ||||||||||
Index | 259 (31.8) | 0 (0.0) | 259 (100.0) | 491 (60.3) | 268 (48.3) | 223 (86.1) | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Spouse | - | - | - | 387 (47.5) | 248 (44.7) | 139 (53.7) | - | 0.02 | - | - |
p‡ | - | - | - | < 0.001 | 0.23 | < 0.001 | - | - | - | - |
Heavy alcohol use¶ | ||||||||||
Index | 34 (4.2) | 28 (5.0) | 6 (2.3) | 34 (4.2) | 28 (5.0) | 6 (2.3) | 0.070 | 0.070 | 1.00 | 1.00 |
Spouse | - | - | - | 30 (3.7) | 26 (4.7) | 4 (1.5) | - | 0.03 | - | - |
p‡ | - | - | - | 0.61 | 0.78 | 0.52 | - | - | - | - |
PSQI, points | ||||||||||
Index | 5.8 (3.14) | 5.5 (2.94) | 6.5 (4.40) | 6.0 (3.32) | 5.9 (3.34) | 6.1 (3.30) | < 0.001 | 0.29 | 0.014 | 0.15 |
Spouse | - | - | - | 6.0 (3.52) | 5.8 (3.47) | 6.5 (3.60) | - | 0.02 | - | - |
p‡ | - | - | - | 0.70 | 0.79 | 0.29 | - | - | - | - |
GDS, points | ||||||||||
Index | 8.6 (5.98) | 8.0 (5.83) | 10.0 (6.10) | 8.1 (6.21) | 7.5 (5.84) | 9.4 (6.77) | < 0.001 | < 0.001 | 0.059 | 0.24 |
Spouse | - | - | - | 8.4 (6.26) | 8.0 (6.0) | 9.3 (6.73) | - | 0.010 | - | - |
p‡ | - | - | - | 0.37 | 0.17 | 0.78 | - | - | - | - |
MMSE, points | ||||||||||
Index | 27.0 (2.64) | 27.0 (2.50) | 27.0 (2.92) | 27.0 (2.95) | 27.0 (2.85) | 27.0 (3.15) | 0.93 | 0.87 | 0.91 | 0.85 |
Spouse | - | - | - | 26.4 (3.30) | 26.3 (3.22) | 26.6 (3.46) | - | 0.34 | - | - |
p‡ | - | - | < 0.001 | < 0.001 | 0.12 | - | - | - | - |