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Fig. 3 | BMC Medicine

Fig. 3

From: The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial

Fig. 3

Green-MED adherence, components, and the association with mAge change. Left: forest plot of GMD adherence score (lower left) and its components (upper left) following 18 months of dietary intervention across groups with between-group differences indicated. Data presented as mean ± SE. Adherence was assessed using a 9-item score, ranging from 0 (non-adherence) to 9 (full adherence). Upper middle: association changes in the corresponding dietary component on the left with relative changes in Li mAge. Lower middle: the association of GMD score and relative change in Li mAge. Upper right: association changes in the corresponding dietary component on the left with relative changes in Hannum mAge. Lower middle: the association of GMD score and relative change in Hannum mAge. Data presented as beta coefficients; multi-variate models adjusted for age, sex, baseline mAge, and weight loss. Red dots = HDG; blue dots MED; green dots = green = MED. *p < 0.05; #p < 0.1

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