Table 1 Baseline characteristics across the intervention groups stratified by sexa
|  | Men (N = 228) | Women (N = 28) | ||||||
|---|---|---|---|---|---|---|---|---|
HDG (N = 78) | MED (N = 72) | Green-MED (N = 78) | p between* | HDG (N = 10) | MED (N = 9) | Green-MED (N = 9) | p between* | |
Aging measurements | ||||||||
 Age, years | 51.0 (10.3) | 51.2 (10.0) | 51.0 (11.1) | 0.95 | 55.3 (10.8) | 56.0 (13.2) | 49.1 (10.1) | 0.43 |
 First generation clocks | ||||||||
  Li mAge, years | 64.4 (8.6) | 63.5 (8.4) | 63.9 (9.1) | 0.72 | 63.7 (7.8) | 69.1 (12.4) | 64.6 (8.7) | 0.63 |
  Horvath mAge, years | 59.3 (9.5) | 58.5 (8.3) | 58.3 (9.5) | 0.57 | 61.5 (9.8) | 61.9 (12.0) | 55.6 (7.1) | 0.32 |
  Hannum mAge, years | 66.9 (9.2) | 65.4 (8.8) | 65.8 (9.6) | 0.64 | 66.7 (8.2) | 69.5 (12.4) | 63.1 (8.2) | 0.51 |
  Horvath skin and blood mAge, years | 62.4 (9.4) | 61.5 (8.7) | 61.4 (9.9) | 0.63 | 66.0 (8.9) | 64.5 (12.1) | 61.5 (9.32) | 0.39 |
 Second-generation clocks | ||||||||
  Levine PhenoAge, years | 43.3 (9.0) | 41.7 (9.2) | 42.9 (11.0) | 0.41 | 46.6 (8.8) | 47.5 (12.3) | 41.2 (7.7) | 0.21 |
  PCGrimAge, years | 65.8 (8.2) | 65.1 (7.9) | 65.4 (9.0) | 0.82 | 65.9 (7.4) | 68.7 (10.9) | 60.8 (7.7) | 0.16 |
 Third-generation clocks (aging pace) | ||||||||
  DunedinPACE | 1.12 (0.1) | 1.09 (0.1) | 1.12 (0.1) | 0.09 | 1.14 (0.1) | 1.17 (0.1) | 1.07 (0.1) | 0.042 |
Anthropometric | ||||||||
 Body mass index, kg/m2 | 31.4 (3.9) | 31.1 (3.8) | 31.1 (3.8) | 0.92 | 30.2 (4.0) | 33.5 (4.5) | 30.3 (3.8) | 0.17 |
 Waist circumference, cm | 110 (9.4) | 111 (9.5) | 110 (8.0) | 0.72 | 102 (7.9) | 107 (8.2) | 98.1 (5.9) | 0.09 |
Lifestyle habits | ||||||||
 Current smoker, % | 17.9% | 6.9% | 15.4% | 0.13 | 20.0% | 22.2% | 22.2% | 1 |
 Diabetics, % | 10.3% | 8.3% | 14.1% | 0.50 | 0% | 22.2% | 0% | 0.19 |
 Fatty liver, % | 60.3% | 59.7% | 60.3% | 0.86 | 30% | 44.4% | 22.2% | 0.67 |
 Metabolic syndrome => 3, % | 70.5% | 54.2% | 66.7% | 0.09 | 10.0% | 66.7% | 22.2% | 0.036 |
 Fish, median intake servings/day | 0.38 | 0.38 | 0.38 | 0.77 | 0.25 | 0.27 | 0.32 | 0.92 |
 Meat, median intake servings/day | 0.59 | 0.48 | 0.55 | 0.45 | 0.44 | 0.54 | 0.34 | 0.42 |
 Fruit, median intake servings/day | 2.66 | 2.24 | 2.77 | 0.84 | 3.14 | 3.38 | 3.57 | 0.51 |
 Vegetables, median intake servings/day | 5.57 | 5.67 | 5.47 | 0.64 | 5.69 | 7.79 | 10.8 | 0.16 |
 Legumes, median intake servings/day | 0.23 | 0.23 | 0.27 | 0.48 | 0.14 | 0.23 | 0.29 | 0.59 |