Table 2 PheWAS using Cox regression was conducted to investigate the relationship between MAFLD and causes of death in males and females
Causes of death | Total (N = 326,606) | Female (N = 122,626) | Male (N = 203,980) | |||
|---|---|---|---|---|---|---|
No.a | HR (95% CI) | No.a | HR (95% CI) | No.a | HR (95% CI) | |
Cardiovascular death | 6025 | 1.64 (1.58–1.71) | 1603 | 1.97 (1.81–2.14) | 4422 | 1.55 (1.48–1.62) |
Digestive system death | 1409 | 1.81 (1.66–1.98) | 441 | 2.30 (1.95–2.73) | 968 | 1.65 (1.49–1.83) |
Endocrine system death | 2007 | 3.23 (2.95–3.53) | 605 | 4.04 (3.38–4.83) | 1402 | 2.97 (2.67–3.29) |
Genitourinary system death | 1203 | 2.05 (1.86–2.26) | 383 | 2.49 (2.07–3.01) | 820 | 1.89 (1.68–2.12) |
Infectious and parasitic death | 867 | 1.63 (1.46–1.80) | 332 | 1.60 (1.35–1.90) | 535 | 1.50 (1.31–1.71) |
Malignant neoplasms death | 7488 | 1.26 (1.21–1.30) | 2556 | 1.28 (1.21–1.36) | 4932 | 1.24 (1.19–1.30) |
Respiratory system death | 3606 | 1.21 (1.15–1.27) | 1070 | 1.50 (1.36–1.65) | 2536 | 1.12 (1.05–1.18) |
Unnatural cause death | 1083 | 1.21 (1.11–1.32) | 280 | 1.45 (1.21–1.75) | 803 | 1.14 (1.03–1.27) |