Fig. 2
Changes in fungal biodiversity in LUAD. A, B Alpha diversity. Chao1 and Shannon indices describe the α-diversity of the fungi in the LUAD and HC groups. Relative to results in controls, the α-diversity was increased significantly in patients with LUAD (P = 0,0043 and P = 0.0217). C Venn diagram analysis of OTU abundance between the two groups. The overlap shows that 155 OTUs were shared between the two groups, while 165 and 127 OTUs were unique for in the LUAD and HC groups, respectively. D Beta diversity. Principal coordinate analysis of Bray–Curtis distance with each sample colored by group. Groups were compared using the Adonis method (Adonis R.2 = 0.0279, P = 0.0040)