Table 3 Association between baseline FABP-4 concentrations and risk of colorectal cancer (conditional logistic regression models)

Overall (1324 cases and matched controls)

 Quintile 1

237/263

1

Reference

1

Reference

1

Reference

 Quintile 2

256/268

1.08

(0.84, 1.38)

1.08

(0.84, 1.40)

1.03

(0.79, 1.33)

 Quintile 3

268/266

1.15

(0.89, 1.49)

1.14

(0.88, 1.48)

1.04

(0.79, 1.36)

 Quintile 4

267/265

1.16

(0.90, 1.49)

1.12

(0.86, 1.45)

0.98

(0.74, 1.29)

 Quintile 5

296/262

1.32

(1.01, 1.72)

1.26

(0.96, 1.66)

1.01

(0.74, 1.38)

 p-trend

0.03

0.08

0.94

 per SD of FABP-4 (8.9 ng/ml)^d

1.10

(1.01, 1.21)

1.09

(0.99, 1.19)

1.01

(0.92, 1.12)

Men (640 cases and matched controls)

 Quintile 1

118/128

1

Reference

1

Reference

1

Reference

 Quintile 2

119/128

1.02

(0.71, 1.45)

1

(0.68, 1.46)

0.89

(0.61, 1.32)

 Quintile 3

139/128

1.20

(0.84, 1.72)

1.21

(0.83, 1.75)

1.02

(0.70, 1.50)

 Quintile 4

127/128

1.09

(0.77, 1.56)

1.04

(0.71, 1.52)

0.85

(0.57, 1.26)

 Quintile 5

137/128

1.19

(0.82, 1.73)

1.11

(0.74, 1.64)

0.76

(0.49, 1.19)

 p-trend

0.35

0.65

0.21

 per SD of FABP-4 (8.9 ng/ml)^d

1.07

(0.93, 1.24)

1.07

(0.92, 1.23)

0.95

(0.80, 1.13)

Women (684 cases and matched controls)

 Quintile 1

119/135

1

Reference

1

Reference

1

Reference

 Quintile 2

137/140

1.13

(0.80, 1.61)

1.14

(0.80, 1.64)

1.14

(0.79, 1.65)

 Quintile 3

129/138

1.11

(0.77, 1.60)

1.12

(0.77, 1.64)

1.08

(0.73, 1.60)

 Quintile 4

140/137

1.23

(0.85, 1.76)

1.22

(0.84, 1.79)

1.15

(0.77, 1.72)

 Quintile 5

159/134

1.45

(0.99, 2.12)

1.46

(0.99, 2.17)

1.34

(0.84, 2.11)

 p-trend

0.05

0.05

0.24

 per SD of FABP-4 (8.9 ng/ml)^d

1.12

(1.00, 1.26)

1.12

(1.00, 1.26)

1.09

(0.95, 1.25)

 p-heterogeneity by sex

0.62

0.57

0.24