Table 2 TRAEs
|  | All patients (N = 19) | Group by administration schedule of MASCT-I | |||||||
|---|---|---|---|---|---|---|---|---|---|
Schedule-I group (N = 9) | Schedule-II group (N = 10) | ||||||||
Grade 1–2 | Grade 3 | Grade 4 | Grades 1–2 | Grade 3 | Grade 4 | Grades 1–2 | Grade 3 | Grade 4 | |
Any | 8 (42.1%) | 10 (52.6%) | 1 (5.3%) | 5 (55.6%) | 4 (44.4%) | 0 | 3 (30.0%) | 6 (60.0%) | 1 (10.0%) |
Neutrophil count decreased | 10 (52.6%) | 3 (15.8%) | 1 (5.3%) | 4 (44.4%) | 1 (11.1%) | 0 | 6 (60.0%) | 2 (20.0%) | 1 (10.0%) |
Hypertriglyceridemia | 13 (68.4%) | 1 (5.3%) | 0 | 7 (77.8%) | 1 (11.1%) | 0 | 6 (60.0%) | 0 | 0 |
Proteinuria | 12 (63.2%) | 1 (5.3%) | 0 | 5 (55.6%) | 0 | 0 | 7 (70.0%) | 1 (10.0%) | 0 |
Hypothyroidism | 12 (63.2%) | 0 | 0 | 5 (55.6%) | 0 | 0 | 7 (70.0%) | 0 | 0 |
Hypercholesterolemia | 10 (52.6%) | 1 (5.3%) | 0 | 5 (55.6%) | 0 | 0 | 5 (50.0%) | 1 (10.0%) | 0 |
WBC count decreased | 10 (52.6%) | 1 (5.3%) | 0 | 3 (33.3%) | 0 | 0 | 7 (70.0%) | 1 (10.0%) | 0 |
Anemia | 10 (52.6%) | 1 (5.3%) | 0 | 5 (55.6%) | 0 | 0 | 5 (50.0%) | 1 (10.0%) | 0 |
Blood bilirubin increased | 10 (52.6%) | 0 | 0 | 5 (55.6%) | 0 | 0 | 5 (50.0%) | 0 | 0 |
Platelet count decreased | 10 (52.6%) | 0 | 0 | 2 (22.2%) | 0 | 0 | 8 (80.0%) | 0 | 0 |
Diarrhea | 10 (52.6%) | 0 | 0 | 4 (44.4%) | 0 | 0 | 6 (60.0%) | 0 | 0 |
Hypertension | 7 (36.8%) | 2 (10.5%) | 0 | 2 (22.2%) | 2 (22.2%) | 0 | 5 (50.0%) | 0 | 0 |
PPE syndrome | 7 (36.8%) | 0 | 0 | 3 (33.3%) | 0 | 0 | 4 (40.0%) | 0 | 0 |
AST increased | 6 (31.6%) | 0 | 0 | 4 (44.4%) | 0 | 0 | 2 (20.0%) | 0 | 0 |
Rash | 6 (31.6%) | 0 | 0 | 2 (22.2%) | 0 | 0 | 4 (40.0%) | 0 | 0 |
GGT increased | 4 (21.1%) | 1 (5.3%) | 0 | 3 (33.3%) | 0 | 0 | 1 (10.0%) | 1 (10.0%) | 0 |
Hyperuricemia | 5 (26.3%) | 0 | 0 | 2 (22.2%) | 0 | 0 | 3 (30.0%) | 0 | 0 |
Headache | 5 (26.3%) | 0 | 0 | 3 (33.3%) | 0 | 0 | 2 (20.0%) | 0 | 0 |
Pyrexia | 5 (26.3%) | 0 | 0 | 1 (11.1%) | 0 | 0 | 4 (40.0%) | 0 | 0 |
Stomatitis | 3 (15.8%) | 1 (5.3%) | 0 | 1 (11.1%) | 1 (11.1%) | 0 | 2 (20.0%) | 0 | 0 |
ALT increased | 4 (21.1%) | 0 | 0 | 2 (22.2%) | 0 | 0 | 2 (20.0%) | 0 | 0 |
RCCEP | 4 (21.1%) | 0 | 0 | 1 (11.1%) | 0 | 0 | 3 (30.0%) | 0 | 0 |
Liver injury | 3 (15.8%) | 0 | 0 | 2 (22.2%) | 0 | 0 | 1 (10.0%) | 0 | 0 |
Blood LDH increased | 3 (15.8%) | 0 | 0 | 0 | 0 | 0 | 3 (30.0%) | 0 | 0 |
Pruritus | 3 (15.8%) | 0 | 0 | 2 (22.2%) | 0 | 0 | 1 (10.0%) | 0 | 0 |
Feeling cold | 3 (15.8%) | 0 | 0 | 3 (33.3%) | 0 | 0 | 0 | 0 | 0 |