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Table 1 Logistic regression of MVI presence based on preoperative data in the training cohort

From: Noninvasive urinary protein signatures combined clinical information associated with microvascular invasion risk in HCC patients

Variable

Univariate logistic OR (95% CI)

Regression P

Multivariate logistic OR (95% CI)

Regression P

Sex, male vs female

0.55 (0.13–2.42)

0.43

  

Age, year

0.99 (0.94–1.03)

0.55

  

Tumor number

0.82 (0.23–2.91)

0.76

  

Tumor diameter, cm

1.26 (1.03–1.55)

0.02

1.197 (0.924–1.552)

0.17

Capsule invasion, Complete vs incomplete

2.27 (0.86–6.03)

0.1

  

WBCs, 109/L

  < 4 vs 4–10

0.83 (0.09–7.68)

0.87

  

 4–10 vs > 10

0.49 (0.08–3.21)

0.46

  

HGB, g/L

  < 120 vs 120–160

1 (0.07–14.64)

1

  

 120–160 vs > 160

1.93 (0.52–7.18)

0.33

  

NEUT, 109/L

  < 2.04 vs 2.04–7.50

1 (0.12–8.31)

1

  

 2.04–7.50 vs > 7.50

0.8 (0.15–4.33)

0.8

  

MONO, 0.12–0.8 vs > 0.8 × 109/L

0.83 (0.11–6.25)

0.86

  

LYMPH, < 0.80 vs 0.80–0.40 × 109/L

2.65 (0.26–26.82)

0.41

  

PLT, 109/L

  < 100 vs 100–300

18781632.9 (0–Inf)

0.99

  

 100–300 vs > 300

13042800.6 (0–Inf)

0.99

  

PT(s), 10.0–13.2 vs > 13.2 S

1.15 (0.35–3.76)

0.82

  

APTT, S

  < 20.9 vs 20.9–34.6

1.33 (0.07–26.62)

0.85

  

 20.9–34.6 vs > 34.6

1.75 (0.15–20.35)

0.65

  

D-D, ≤ 0.55 vs > 0.55 mg/L FEU

0.42 (0.14–1.28)

0.13

  

GLU, mmol/L

  < 3.89 vs 3.89–6.38

0 (0–Inf)

0.99

  

 3.89–6.38 vs > 6.38

1.26 (0.43–3.7)

0.67

  

CRE, µmol/L

  < 57.0 vs 57.0–97.0

1.67 (0.19–14.27)

0.64

  

 57.0–97.0 vs > 97.0

1.44 (0.31–6.62)

0.64

  

ALB, < 40.0 vs 40.0–55.0 g/L

0.79 (0.27–2.31)

0.66

  

ALT, U/L

  < 9.0 vs 9.0–50.0

5,182,031.57 (0–Inf)

0.99

  

 9.0–50.0 vs > 50.0

0.64 (0.22–1.87)

0.42

  

AST, U/L

  < 15.0 vs 15.0–40.0

0.9 (0.05–16.6)

0.94

  

 15.0–40.0 vs > 40.0

0.67 (0.23–1.94)

0.46

  

GGT, 10.0–60.0 vs > 60.0

3.75 (0.29–47.99)

0.03

2.643 (0.04–179.11)

0.03

TBIL, 2–21 vs > 21 µmol/L

1.05 (0.26–4.32)

0.94

  

DBIL, ≤ 5.1 vs > 5.1

0.88 (0.32–2.42)

0.8

  

ALP, U/L

  < 45.0 vs 45.0–125.0

4 (0.21–75.66)

0.36

  

 45.0–125.0 vs > 125.0

1.69 (0.29–9.94)

0.56

  

CRP, ≤ 0.6 vs > 0.6 mg/dl

1.08 (0.26–4.46)

0.91

  

AFP, ≤ 200 vs > 200 ng/ml

2.99(1.04–8.57)

0.04

6.268 (1.40–28.09)

0.02

CA199, ≤ 27 vs > 27 U/ml

0.58 (0.2–1.67)

0.32

  

CEA, ≤ 5.0 vs > 5.0 ng/ml

0.65 (0.18–2.38)

0.52

  

HBsAg, positive vs negative

1.76 (0.57–5.49)

0.33

  

HBsAb, Positive vs negative

1.25 (0.39–4.06)

0.71

  

HBeAg, Positive vs negative

0.87 (0.27–2.85)

0.82

  

HBcAb, Positive vs negative

1.57 (0.41–5.98)

0.5

  

Anti-HCV, Positive vs negative

1.21 (0.23–6.49)

0.82

  

Protein score, High vs low

2.72 (1.69–4.38)

0.0001

14.39 (3.47–59.65)

0.0001