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Table 2 Tumor response with anlotinib in RM-NPC according to RECIST v.1.1

From: Anlotinib as a third-line or further treatment for recurrent or metastatic nasopharyngeal carcinoma: a single-arm, phase 2 clinical trial

Responses

FAS (n = 39)

PPS (n = 36)

Best overall response, no.; % (95% CI)

CR

0; 0 (0 to 9.0)

0; 0 (0 to 9.7)

PR

8; 20.5 (9.3 to 36.5)

8; 22.2 (10.1 to 39.2)

SD

20; 51.3 (34.8 to 67.6)

20; 55.6 (38.1 to 72.1)

PD

8; 20.5 (9.3 to 36.5)

8; 22.2 (10.1 to 39.2)

NA

3; 7.7 (1.6 to 20.9)

0; 0 (0 to 9.7)

ORR, n (%)

8; 20.5 (9.3 to 36.5)

8; 22.2 (10.1 to 39.2)

DCR, n (%)

28; 71.8 (55.1 to 85.0)

28; 77.8 (60.8 to 89.9)

  1. CR Complete response, DCR Disease control rate, FAS Full analysis set, NA Not assessable, ORR Objective response rate, PD Progressive disease, PPS Per-protocol set, PR Partial response, SD Stable disease