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Table 2 The top 20 significant metabolites associated with cumulative average alcohol consumption

From: Circulating metabolites may illustrate relationship of alcohol consumption with cardiovascular disease

Metabolites

Beta

SE

P value

CE 16:1

0.023

0.002

6.30E − 45

PC 32:1

0.021

0.002

3.10E − 38

PC 34:1

0.019

0.002

5.99E − 30

PC-B 36:4

0.017

0.002

5.18E − 24

TAG 54:4

 − 0.017

0.002

6.17E − 22

PC 32:0

0.015

0.002

1.13E − 19

CE 20:5

0.014

0.002

1.14E − 17

LPC 20:5

0.013

0.002

2.17E − 15

TAG 52:4

 − 0.013

0.002

9.05E − 15

TAG 54:5

 − 0.013

0.002

1.18E − 14

TAG 52:3

 − 0.013

0.002

1.58E − 14

TAG 48:0

0.012

0.002

1.74E − 13

Fumarate-malate

0.012

0.002

7.00E − 13

SM 24:1

0.012

0.002

5.17E − 12

Dimethylglycine

 − 0.010

0.001

7.48E − 12

Xanthurenate

0.011

0.002

3.53E − 11

PC 34:4

0.011

0.002

9.52E − 11

TAG 52:5

 − 0.011

0.002

4.81E − 10

PC 36:3

0.010

0.002

7.39E − 10

  1. Top 20 out of 60 metabolites significantly associated with the cumulative average total alcohol consumption (p < 0.00024) adjusting for age, sex, batch, smoking status, BMI, physical activity index and diet score as fixed effect,  and family relationship as random effect