Table 1 Sample characteristics at < 60, 60 to < 70, and ≥ 70 years overall and according to dementia status at the end of follow-up (31 March 2019)
At age < 60 years | At ages 60 years to < 70 years | At age ≥ 70 years | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total population | Dementia | p | Total population | Dementia | p | Total population | Dementia | p | ||||
No | Yes | No | Yes | No | Yes | |||||||
Age, M(SD) | 55.0 (3.0) | 55.0 (3.0) | 56.3 (2.6) | < 0.01 | 65.0 (1.5) | 65.0 (1.5) | 64.9 (1.7) | 0.33 | 73.9 (1.9) | 73.9 (1.9) | 74.2 (1.9) | 0.01 |
Sex, women | 2160 (30.4) | 2007 (30.0) | 153 (37.3) | < 0.01 | 1849 (28.8) | 1717 (28.5) | 132 (34.8) | 0.01 | 1036 (29.1) | 945 (28.6) | 91 (34.7) | 0.04 |
Education, low | 3179 (44.7) | 2950 (44.0) | 229 (55.9) | < 0.01 | 2791 (43.5) | 2579 (42.8) | 212 (55.9) | < 0.01 | 1747 (49.0) | 1594 (48.3) | 153 (58.4) | < 0.01 |
Ethnicity, non-white | 711 (10.0) | 647 (9.7) | 64 (15.6) | < 0.01 | 543 (8.5) | 488 (8.1) | 55 (14.5) | < 0.01 | 346 (9.7) | 307 (9.3) | 39 (14.9) | < 0.01 |
Marital status, married | 5426 (76.3) | 5125 (76.5) | 301 (73.4) | 0.44 | 4889 (76.3) | 4616 (76.5) | 273 (72.0) | 0.20 | 2564 (71.9) | 2400 (72.7) | 164 (62.6) | 0.01 |
Smoking, current smokers | 842 (11.8) | 789 (11.8) | 53 (12.9) | 0.46 | 414 (6.5) | 383 (6.4) | 31 (8.2) | 0.05 | 107 (3.0) | 102 (3.1) | 5 (1.9) | 0.52 |
Alcohol, moderate drinkers | 3795 (53.4) | 3608 (53.9) | 187 (45.6) | < 0.01 | 3450 (53.8) | 3262 (54.1) | 188 (49.6) | < 0.01 | 1964 (55.1) | 1836 (55.6) | 128 (48.9) | < 0.01 |
Fruits and vegetables, ≥ 2/day | 2171 (30.5) | 2091 (31.2) | 80 (19.5) | < 0.01 | 3018 (47.1) | 2893 (48.0) | 125 (33.0) | < 0.01 | 1786 (50.1) | 1700 (51.5) | 86 (32.8) | < 0.01 |
PA, h/week, M(SD) | 3.3 (3.6) | 3.3 (3.6) | 3.0 (3.9) | < 0.01 | 4.0 (3.6) | 4.0 (3.6) | 3.4 (3.3) | < 0.01 | 3.5 (3.3) | 3.6 (3.3) | 3.2 (3.3) | 0.02 |
Prevalence of CVD | 383 (5.4) | 357 (5.3) | 26 (6.3) | 0.38 | 774 (12.1) | 721 (12.0) | 53 (14.0) | 0.24 | 799 (22.4) | 725 (22.0) | 74 (28.2) | 0.02 |
Body mass index, M(SD) | 26.3 (4.0) | 26.3 (4.0) | 26.3 (4.1) | 0.31 | 26.8 (4.3) | 26.8 (4.3) | 26.6 (4.2) | 0.30 | 26.9 (4.3) | 26.9 (4.3) | 26.7 (4.6) | 0.22 |
Metabolic components | ||||||||||||
Elevated triglycerides | 2184 (30.7) | 2057 (31.0) | 127 (31.0) | 0.91 | 2559 (39.9) | 2421 (40.1) | 138 (36.4) | 0.15 | 1914 (53.7) | 1771 (53.6) | 143 (54.6) | 0.77 |
Low HDL-C | 1069 (15.0) | 986 (14.7) | 83 (20.2) | < 0.01 | 1904 (29.7) | 1802 (29.9) | 102 (26.9) | 0.22 | 1748 (49.1) | 1619 (49.0) | 129 (49.2) | 0.95 |
Elevated blood pressure | 3187 (44.8) | 2970 (44.3) | 217 (52.9) | < 0.01 | 3756 (58.6) | 3534 (58.6) | 222 (58.6) | 0.99 | 2581 (72.4) | 2386 (72.3) | 195 (74.4) | 0.45 |
Elevated fasting glucose | 1636 (23.0) | 1538 (23.0) | 98 (24.0) | 0.64 | 1682 (26.2) | 1568 (26.0) | 114 (30.1) | 0.08 | 976 (27.4) | 884 (26.8) | 92 (35.1) | < 0.01 |