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Fig. 4 | BMC Medicine

Fig. 4

From: Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study

Fig. 4

Risk stratification of post-radiation nasopharyngeal necrosis using the radiomic signature. A–C Cumulative incidences of post-radiation nasopharyngeal necrosis (PRNN) in the training (A), internal validation (B), and external validation (C) cohorts. D–E Cumulative PRNN incidences in patients with small (D) and large (E) tumors. Hazard ratios (HRs) were estimated using univariate Cox regression analyses. GTV gross tumor volume, CI confidence interval

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