Table 1 GWAS Summary Statistics of Blood/Urine Biomarkers utilised for cross-trait analysis with endometriosis
Trait | Female-specific | Ancestry and sample size | Publication (GWAS Catalog Accession Number) |
|---|---|---|---|
Apolipoprotein A | No | 311,601 European ancestry individuals, 5550 African ancestry individuals, 6682 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019495 |
Apolipoprotein B | No | 340,860 European ancestry individuals, 5962 African ancestry individuals, 7275 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019496 |
Alanine aminotransferase | No | 342,387 European ancestry individuals, 6017 African ancestry individuals, 7325 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019492 |
Testosterone | Yes | 230,454 European ancestry women | Ruth, Day [14] GCST90012112 |
Bioavailable Testosterone | Yes | 188,507 European ancestry women | Ruth, Day [14] GCST90012102 |
Triglycerides (for Genetic Correlation) | No | 1,320,016 European ancestry individuals | Graham, Clarke [16] GCST90239664 |
Triglycerides (for MR) | No | 115,082 European ancestry individuals | Richardson, Sanderson [17] GCST90092992 |
Urate | No | 342,087 European ancestry individuals, 6011 African ancestry individuals, 7328 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019524 |
HDL Cholesterol | No | 313,372 European ancestry individuals, 5573 African ancestry individuals, 6689 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019510 |
LDL Cholesterol | No | 341,875 European ancestry individuals, 6003 African ancestry individuals, 7319 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019512 |
Sex hormone-binding globulin | Yes | 189,473 European ancestry women | Ruth, Day [14] GCST90012107 |
Albumin | No | 313,032 European ancestry individuals, 5573 African ancestry individuals, 6687 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019493 |
Calcium | No | 313,387 European ancestry individuals, 5576 African ancestry individuals, 6696 South Asian ancestry individuals | Sinnott-Armstrong, Tanigawa [12] GCST90019500 |