Fig. 1From: Genetically predicted plasma levels of amino acids and metabolic dysfunction-associated fatty liver disease risk: a Mendelian randomization studySchematic overview of the study design and MR analysis. a. rs3970551 was absent from the IV set in the replication MAFLD GWAS by Anstee et al. due to non-available proxy SNPs being identified. A The causal diagram of the relationship between circulating amino acids and MAFLD investigated in the two-sample MR analysis. B The data source of amino acids and MAFLD and relevant information on genetic instrumental variables selected as well as statistical analysis methods used in the study. GWAS, genome-wide association study; IV, instrumental variable; IVW, inverse variance weighted; MAFLD, metabolic dysfunction-associated fatty liver disease; MR, Mendelian randomizationBack to article page