Skip to main content
Fig. 4 | BMC Medicine

Fig. 4

From: Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease

Fig. 4

Two-step network mediation analysis connecting the obesity measures and lifestyle factors to coronary artery disease through the modulation of specific circulating proteins. A The overview of potential causal mediating network. B The proportion of the association between obesity and coronary artery disease mediated by circulating proteins. C The proportion of the association between of physical activity and sedentary behaviors with coronary artery disease mediated by circulating proteins. D The frequency of circulating proteins involved in the mediating network connecting modifiable factors to CAD risk. Abbreviations: BMI, body mass index; VAT, visceral adipose tissue; VPA, vigorous physical activity; WHR, waist-to-hip ratio; WC, waist circumference

Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us