Table 1 Baseline characteristics of participants in the UK Biobank (N = 340,631)

PC

 No

112,905 (99.5)

113,497 (99.7)

113,100 (99.8)

116,096 (99.6)

101,907 (99.7)

121,499 (99.8)

 Yes

526 (0.5)

361 (0.3)

242 (0.2)

509 (0.4)

339 (0.3)

281 (0.2)

Age, median (IQR), year

57 (50–63)

58 (50–63)

56 (49–62)

58 (50–63)

57 (50–63)

56 (49–62)

Sex

   Female

58,355 (51.4)

58,607 (51.5)

58,235 (51.3)

44,499 (38.2)

53,212 (52.0)

77,486 (63.6)

   Male

55,076 (48.6)

55,251 (48.5)

55,107 (48.6)

72,106 (61.8)

49,034 (48.0)

44,294 (36.4)

Education level

 College or University

31,371 (27.7)

39,433 (34.6)

48,797 (43.1)

34,789 (29.8)

35,529 (34.7)

49,283 (40.5)

 Upper secondary

13,128 (11.6)

13,940 (12.2)

14,080 (12.4)

13,998 (12.0)

12,243 (12.0)

14,907 (12.2)

 Lower secondary

33,978 (30.0)

31,126 (27.3)

27,468 (24.2)

33,626 (28.8)

28,155 (27.5)

30,791 (25.3)

 Vocational

8,615 (7.6)

7,496 (6.6)

6,187 (5.5)

9,252 (7.9)

6,623 (6.5)

6,423 (5.3)

 Other

26,339 (23.2)

21,863 (19.2)

16,810 (14.8)

24,940 (21.4)

19,696 (19.3)

20,376 (16.7)

Socioeconomic status

 Low

28,469 (25.1)

20,473 (18.0)

19,187 (16.9)

26,114 (22.4)

19,494 (19.1)

22,521 (18.5)

 Middle

65,294 (57.6)

69,446 (61.0)

69,548 (61.4)

68,529 (58.8)

61,707 (60.4)

74,052 (60.8)

 High

19,668 (17.3)

23,939 (21.0)

24,607 (21.7)

21,962 (18.8)

21,045 (20.6)

25,207 (20.7)

PRS

 Low

37,640 (33.2)

38,161 (33.5)

37,724 (33.3)

38,792 (33.3)

34,148 (33.4)

40,585 (33.3)

 Intermediate

37,798 (33.3)

37,958 (33.3)

37,815 (33.4)

38,773 (33.3)

34,203 (33.5)

40,595 (33.3)

 High

37,993 (33.5)

37,739 (33.1)

37,803 (33.4)

39,040 (33.5)

33,895 (33.2)

40,600 (33.3)