Fig. 2

Maternal sevoflurane exposure results in abnormal behaviors in adolescent offspring. A Experimental procedures. B The representative traces in the OFT within 10 min. C The representative traces in the EPM in 5 min. D–G Comparisons about the total distance traveled (D), the central distance traveled (E), the total number of central visits (F), and the percentage of time spent in the central area (G), p=0.02390, 0234, 0.0161, and 0.0431, respectively. Ctr: n=20; Sevo: n=16. H-J Comparisons about the total number of arm entries (p=0.0429) (H), the ratio of the number of open arm entries and total arm entries (I), and the ratio of the duration in open arm and total time (J). Ctr: n=20; Sevo: n=16. K The immobile time in the TST, p=0.0071. Ctr: n=21; Sevo: n=19. The data are represented as mean ± SEM. Two-tailed Student’s t-test was performed for statistical analysis. *p < 0.05, **p < 0.01