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Table 1 Study and participant characteristics

From: A systematic review and meta-analysis of short-stay programmes for total hip and knee replacement, focusing on safety and optimal patient selection

First author, year of publication

Country

Surgical procedure (% intervention group)

Number of participants: n

% Female

Mean (SD) or median [IQR] age in years

Brief description of short-stay intervention

Brief description of usual care

Maximum study follow-up time

Randomised controlled trials (parallel arm design)

 Fransen et al. 2018 [57]

Netherlands

TKR

Short-stay: 25

Usual care: 24

Short-stay: 56

Usual care: 37

Short-stay: 64 (9)

Usual care: 61 (7)

- Mean LoS 2 days

- No tourniquet, intra-operative local infiltration and analgesia, no pain pumps, wound drains, or bladder catheters were used

- Mean LoS 4 days

- Regular hospital TKR protocol, including the use of a tourniquet, wound drains, and bladder catheter

12 weeks

 Petersen et al. 2006 [61]

Denmark

THR

Short-stay: 27

Usual care: 30

Short-stay: 56

Usual care: 47

Median [range]

Short-stay: 55 [28–84]

Usual care: 58 [26–81]

- No difference found in the LoS

- Received an optimisation pack involving pre- and post-operative strategies in addition to usual care

- No difference found in the LoS

- Standard pre- and post-operative multimodal anaesthesia and analgesia

30 days

 Reilly et al. 2005 [33]

United Kingdom

Unicompartmental knee replacement

Short-stay: 21

Usual care: 20

Short-stay and usual care: 41

Short-stay and usual care: 63

- Mean Los 1.5 days

- Facilitated discharge and discharge support in addition to usual care

- Mean LoS 1.5 days

- Standard surgical, anaesthetic, and analgesic protocol

6 weeks

Registry studies

 Berg et al. 2018 [65]

Sweden

THR (56)

TKR (44)

Short-stay: 7,270

Usual care: 6,640

Short-stay: 57

Usual care: 57

Short-stay: 70 (10)

Usual care: 70 (10)

- Median LoS 3 days for THR and TKR

- Admission on the day of surgery, early mobilisation, functional discharge, LoS ≤ 3 days

- Median LoS 5 days for THR and TKR

- Minimum of written and oral patient information, multimodal analgesia, tranexamic acid

3 months

 Berg et al. 2021 [64]

Sweden

THR (53)

TKR (47)

Short-stay: 67,672

Usual care: 48,621

Short-stay: 56

Usual care: 58

Short-stay THR: 68 (10)

Usual care THR: 69 (10)

Short-stay TKR: 69 (9)

Usual care TKR: 70 (9)

- Median LoS 3 days for THR and TKR

- Admission on the day of surgery, early mobilisation, functional discharge, LoS ≤ 3 days

- Median LoS 5 days for THR and TKR

- Minimum of written and oral patient information, multimodal analgesia, tranexamic acid

90 days

Interrupted time series studies

 Alvis et al. 2021 [38]

United States

THR (33)

TKR (67)

Short-stay: 186

Usual care: 96

Short-stay: 9

Usual care: 12

Short-stay: 65 (9)

Usual care: 63 (9)

- Median LoS 2 days

- Involvement of the Anaesthesia Perioperative Care Service for patients in the presurgical and post-discharge period

- Median LoS 3 days

- Preoperative, intraoperative, and postoperative patient care in the hospital only

30 days

 Amlie et al. 2016 [71]

Norway

THR

Short-stay: 239

Usual care: 4,167

Short-stay: 72

Usual care: 67

Female: 71 (10)

Male: 67 (11)

- LoS not reported

- Four main components: (1) local anaesthetic, (2) cessation of negative vacuum suction drain, (3) early mobilisation, (4) standardised pain management

- LoS not reported

- Patients who received only the standardised pain management protocol

3 days

 Arshad et al. 2014 [25]

England

THR (50)

TKR (50)

Short-stay: 48

Usual care: 48

Short-stay: 40

Usual care: 65

Short-stay: 76 [68–82]

Usual care: 75 [67–82]

- Median LoS 4 days

- Preoperative education, regional anaesthesia, early mobilisation, and avoidance of drains and catheters

- Median LoS 5 days

- No education on patient LoS, post-operative physiotherapy commenced the day after surgery

6 weeks

 Azam et al. 2022 [69]

India

Bilateral TKR

Short-stay: 275

Usual care: 190

Short-stay: 72

Usual care: 66

Short-stay: 66 (9)

Usual care: 66 (10)

- Median LoS 3.9 days

- 9 evidence-based interventions across the pre-operative, intraoperative, and postoperative period

- Median LoS 7.5 days

- No usual care patients had any peripheral nerve blocks post-operatively, and epidural catheters were left in place for 24 h

6 weeks

 Chung et al. 2021 [45]

China

THR (47)

TKR (53)

Short-stay: 111

Usual care: 117

Short-stay: 60

Usual care: 67

Short-stay: 70 (9)

Usual care: 68 (12)

- Mean LoS 3.28 days

- Higher dose of IV steroids, optimised management of pain, nausea and vomiting, blood management, sleep management, and same-day rehabilitation

- Mean LoS 5.16 days

- Usual care patients received generally similar treatment to short-stay patients (except for the specific short-stay components listed), but these treatments are not described

30 days

 de Carvalho Almeida et al. 2021 [67]

Brazil

THR including same-day bilateral surgery

Short-stay: 47

Usual care: 51

Short-Stay: 57

Usual care: 51

n (%)

Short-stay: ≤ 49: 15 (32)

Usual care: ≤ 49: 13 (25)

Short-stay: 50–59: 16 (34)

Usual care: 50–59: 17 (33)

Short-stay: ≥ 60: 16 (34)

Usual care: ≥ 60: 21 (41)

- Mean LoS 2.3 days

- Patient education and multidisciplinary care mandatory, the introduction of tranexamic acid, no opioids or bladder catheters, peri-articular injection, no ICU support, and early mobilisation

- Mean LoS 6.4 days

- No detailed information about the surgery, multidisciplinary approach not encouraged, opioids routinely used, bladder catheter routinely used, ICU support mandatory, functional rehabilitation commenced on the first or second postoperative day. No functional discharge criteria

3 months

 den Hartog et al. 2013 [55]

Netherlands

THR

Short-stay: 384

Usual care: 157

Short-stay: 69

Usual care: 68

Short-stay: 71 (10)

Usual care: 71 (10)

- Mean LoS 2.9 days

- 10 evidence-based interventions across the pre-operative, intraoperative, and postoperative period

- Mean LoS 4.6 days

- Functional discharge criteria, sufficient pain treatment required before discharge (encompassing 2/10 interventions)

3 months

 Dhawan et al. 2017 [26]

England

TKR

Short-stay: 50

Usual care: 70

Short-stay: 42

Usual care: 40

Median [range]

Female: 70 [42–90]

Male: 72 [55-81]

- LoS reduced by 1.5 days in both males and females

- Local anaesthetic, tourniquets released before closure, homeostasis obtained, no drains used

- LoS not reported

- No usual care components reported

During admission

 Didden et al. 2019 [56]

Netherlands

TKR

Short-stay: 85

Usual care: 85

Short-stay: 60

Usual care: 64

Mean [range]

Short-stay: 69 [52–86]

Usual care: 69 [47–86]

- Median LoS 4 days

- Local infiltration analgesia, oxycodone as needed only, mobilisation started 4 h after surgery, targeted discharge as soon as possible after surgery

- Median LoS 7 days

- Epidural analgesia or femoral nerve block, prolonged-release oxycodone for a maximum of 10 days post-discharge, mobilisation started the day after surgery, targeted discharge 4 days after surgery

90 days

 Doman et al. 2012 [39]

United States

THR (39)

TKR (61)

Short-stay: 90

Usual care: 85

Short-stay: 38

Usual care: 58

Short-stay: 62

Usual care: 59

- Mean LoS 2.6 days

- Patient education was used to guide recovery expectations, preoperative pain medication was initiated the morning of surgery, IV sedation was encouraged, efforts were made to use the minimal incision length and early mobilisation

- Mean LoS 5.5 days

- No preoperative analgesia, the surgical technique did not emphasise smaller incisions, no established pain regimen, patients discharged once the pain was controlled via oral medication

30 days

 Dwyer et al. 2012 [37]

United Kingdom

THR

Short-stay: 64

Usual care: 63

Short-stay: 58

Usual care: 65

Short-stay: 70.1 (8.8)

Usual care: 72.5 (8.7)

- Mean LoS 5.3 days

- Preadmission, preoperative, intraoperative, and postoperative interventions but with a focus on preoperative and postoperative nutrition

- Mean LoS 8.3 days

- Usual care pathway not reported

Not reported, but outcomes are provided up to 81 days postop

 Dwyer et al. 2014 [27]

United Kingdom

TKR

Short-stay: 57

Usual care: 55

Short-stay: 70

Usual care: 60

Short-stay: 71 (9)

Usual care: 73 (9)

- Mean LoS 6 days

- Preadmission interventions of multidisciplinary and holistic care and family involvement, and 10 evidence-based interventions across the pre-operative, intraoperative, and postoperative period

- Mean LoS 7.8 days

- Patients admitted the evening before surgery, spinal or general anaesthesia used, mobilisation not started until the day after surgery, no routine physiotherapy

3 weeks

 Featherall et al. 2018 [40]

United States

THR

Short-stay: 2,081

Usual care: 1,033

Short-stay: 50

Usual care: 50

Short-stay: 64 (12)

Usual care: 64 (12)

- Mean LoS 2.55 days

- Preoperative assessment and risk factor modification, antibiotic prophylaxis, tranexamic acid, operating room adjustments, and standardised postoperative care

- Mean LoS 3.21 days

- Usual care pathway not described

90 days

 Galbraith et al. 2017 [70]

Ireland

THR (40)

TKR (60)

Short-stay: 165

Usual care: 145

Short-stay: 42

Usual care: 48

Not reported

- Mean LoS 5.1 days

- Multidisciplinary care, optimisation of pre-existing conditions, drains not used, local infiltration analgesia, tranexamic acid, early mobilisation

- Mean LoS 8.79 days

- Admitted the day before surgery, spinal or general anaesthesia used, analgesics provided, opioids commonly used for pain, mobilisation 1-day post-surgery

90 days

 Gleicher et al. 2021 [58]

Canada

TKR

Short-stay: 383

Usual care: 232

Short-stay: 60

Usual care: 64

Short-stay: 67 (10)

Usual care: 66 (10)

- Mean LoS 2.13 days

- Postoperative analgesia, nausea and vomiting prophylaxis, Foley catheterisation, patient education

- Mean LoS 2.81 days

- Perioperative placement of adductor canal block, IV dexamethasone, avoid unnecessary Foley catheterization, patient education not a focus

30 days

 Gwynne-Jones 2017 [62]

New Zealand

THR (61)

TKR (39)

Short-stay: 528

Usual care: 507

Short-stay: 54

Usual care: 54

Short-stay THR: 68 (12)

Usual care THR: 67 (12)

Short-stay TKR: 70 (9)

Usual care TKR: 70 (9)

- Mean LoS THR 4.3 days

- Mean LoS TKR 4.8 days

- Optimisation of pre-existing conditions, patient education, standardised anaesthesia and analgesia, blood management, early mobilisation

- Mean LoS THR 5.6 days

- Mean LoS TKR 5.7 days

- Usual care pathway not described

90 days

 Harkouk et al. 2021 [49]

France

THR (13)

TKR (27)

Short-stay: 203

Usual care: 294

Short-stay: 66

Usual care: 67

Short-stay THR: 66 (14)

Usual care THR: 68 (12)

Short-stay TKR: 68 (12)

Usual care TKR: 71 (11)

- Mean LoS THR 8.2 days

- Mean LoS TKR 7.1 days

- Staff education

- Mean LoS THR 8.2 days

- Mean LoS TKR 8.7 days

- No staff education

30 days

 Joo et al. 2022 [66]

Australia

THR (34)

TKR (66)

Short-stay: 146

Usual care: 143

Short-stay: 49

Usual care: 50

Short-stay: 69 (9)

Usual care: 69 (9)

- Mean LoS 2.29 days

- Early mobilisation, functional discharge criteria

- Mean LoS 3.24 days

- Mobilisation the day post-surgery, no functional discharge criteria

3 months

 Khan et al. 2014 [28]

United Kingdom

THR (42)

TKR (58)

Short-stay: 3000

Usual care: 3000

Short-stay: 54

Usual care: 51

Short-stay: 68 (10)

Usual care: 69 (10)

- Mean LoS 3 days

- Pharmacological (low-dose spinal anaesthesia), procedural (early mobilisation), and behavioural (Patient and staff education) interventions

- Mean LoS 6 days

- Pharmacological (general anaesthesia), procedural (catheterisation and next-day mobilisation), and behavioural (generic patient and staff education) interventions

90 days

 Larsen et al. 2008 [60] 

Denmark

THR

TKR

Short-stay: 142

Usual care: 105

Not reported

No reported

- Mean LoS 4.4 days

- Preoperative assessment and information, nutrition optimisation, early mobilisation

- Mean LoS 8.8 days

- Patients received identical operation procedures, pain relief medication, and nausea controls

90 days

 Maempel et al. 2015 [30]

United Kingdom

TKR

Short-stay: 84

Usual care: 81

Short-stay: 50

Usual care: 54

Short-stay: 70 (9)

Usual care: 70 (11)

- Mean LoS 3 days

- Patient education, spinal anaesthesia, tranexamic acid, early mobilisation

- Mean LoS 4 days

- Spinal anaesthesia, tranexamic acid, patient-controlled analgesia

During admission

 Maempel et al. 2016 [29]

United Kingdom

THR

Short-stay: 550

Usual care: 611

Short-stay: 62

Usual care: 60

Short-stay: 64 [16]

Usual care: 66 [15]

- LoS reduced by a mean of 1.5 days

- Patient education, functional discharge criteria, spine anaesthetic, early mobilisation

- LoS not reported

- Post-controlled analgesia, mobilisation 1-day post-surgery, a spine anaesthetic,

During admission

 Malviya et al. 2011 [31]

United Kingdom

THR (42)

TKR (58)

Short-stay: 1500

Usual care: 3000

Short-stay: 53

Usual care: 51

Short-stay: 68

Usual care: 69

- Mean LoS 3 days

- Targeted patient and staff education, low-dose spinal anaesthesia, tranexamic acid, local anaesthetic, early mobilisation, functional discharge criteria

- Mean LoS 6 days

- Generic patient and staff education, general anaesthesia, catheterisation, mobilisation 1-day post-surgery, patient-controlled analgesia

60 days

 McDonald 2012 [32]

United Kingdom

TKR

Short-stay: 1081

Usual care: 735

Short-stay: 59

Usual care: 42

Short-stay: 69 (11)

Usual care: 71 (13)

- Mean LoS 4 days

- Patient education, perioperative multimodal analgesia, local intra-articular injection, and early mobilisation

- Mean LoS 6 days

- Tranexamic acid, spinal anaesthesia, mobilisation 1-day post-surgery

90 days

 Picart et al. 2021 [50]

France

TKR

Short-stay: 216

Usual care: 335

Short-stay: 63

Usual care: 66

Short-stay: 69 (8)

Usual care: 69 (10)

- Mean LoS 6.12 days

- Patient education, no perineural block, tourniquet, or drainage, tranexamic acid, early mobilisation

- Mean LoS 6.30 days

- Surgery under perineural block and tourniquet, post-operative drainage

90 days

 Raphael et al. 2011 [59]

Canada

THR (57)

TKR (43)

Short-stay: 100

Usual care: 100

Short-stay: 48

Usual care: 53

Short-stay: 65 (9)

Usual care: 69 (8)

- Mean LoS 47 h

- Patient education, pre-emptive analgesia, patient-controlled opioid analgesia, early mobilisation, and functional discharge criteria

- Mean LoS 116 h

- Limited patient education, no standardised pre or post-operative multimodal analgesia, use of peripheral nerve block for postoperative analgesia mobilisation 1-day post-surgery

30 days

 Romano et al. 2021 [53]

Italy

THR (52)

TKR (48)

Short-stay: 122

Usual care: 59

Short-stay: 45

Usual care: 53

Short-stay: 70 [64-77]

Usual care: 73 [68-77]

- Median LoS 5 days

- Preadmission care, preoperative and intraoperative care, and postoperative care with a focus on patient education, anaesthesia and pain control, wound management and early mobilisation

- Median LoS 8 days

- No patient education, no standard protocol for oral analgesia, conventional anaesthesia and sedation, no prevention of postoperative nausea and vomiting, mobilisation 1-day post-surgery

1 month

 Savaridas et al. 2013 [34]

United Kingdom

THR (42)

TKR (58)

Short-stay: 1,500

Usual care: 3,000

Short-stay: 53

Usual care: 51

Short-stay: 68

Usual care: 69

- Length of stay not reported

- Targeted patient and staff education, low-dose spinal anaesthesia, tranexamic acid, local anaesthetic, early mobilisation, functional discharge criteria

- Length of stay not reported

- Generic patient and staff education, general anaesthesia, catheterisation, mobilisation 1-day post-surgery, patient-controlled analgesia

3 months

 Stambough et al. 2015 [41]

United States

THR

Short-stay: 488

Usual care: 281

Short-stay: 49

Usual care: 55

Short-stay: 55 [45-64]

Usual care: 59 [51-67]

- Median LoS 2 days

- Five targets of patient education (mandatory), pain (intra-op, no opioids), mobilisation (early mobilisation), anaesthesia (patient-specific spinal), and nursing (staff coordination)

- Median LoS 4 days

- No patient education, patient-controlled analgesia, mobilisation delayed, general anaesthesia, and nursing not integrated into postoperative care

30 days

 Starks et al. 2014 [35]

England

THR (41)

TKR (59)

Short-stay: 2,128

Usual care: 2,065

Short-stay: 65

Usual care: 66

Mean [range]

Short-stay: 71 [28–93]

Usual care: 72 [26–98]

- Median LoS TKR 4 days

- Median LoS THR 4 days

- Patient education, spinal anaesthetic, normothermia, standardised analgesic ladder, and early mobilisation

- Median LoS TKR 6 days

- Median LoS THR 6 days

- Usual care pathway not reported

30 days

 Stowers et al. 2016 [63]

New Zealand

THR (31)

TKR (69)

Short-stay: 100

Usual care: 100

Short-stay: 53

Usual care: 59

Short-stay: 67 (9)

Usual care: 65 (13)

- Mean LoS 4 days

- Short-stay pathway details located in supplementary material are no longer accessible

- Mean LoS 5 days

- Usual care pathway details located in supplementary material are no longer accessible

30 days

 Tasso et al. 2022 [54]

Italy

THR (69)

TKR (31)

Short-stay: 2,806

Usual care: 2,236

Short-stay: 57

Usual care: 56

Short-stay: 69 (7)

Usual care: 67 (8)

- Mean LoS 5.1 days

- Pre-admission evaluation, hospital admission, surgical strategies, anaesthesia, blood management, and early mobilisation

- Mean LoS 10.4 days

- Usual care pathway not reported

30 days

 Taylor et al. 2022 [42]

United States

THR (33)

TKR (31)

Short-stay: 279

Usual care: 294

Short-stay: 67

Usual care: 66

Short-stay: 61 (10)

Usual care: 61 (10)

- Mean LoS 1.6 days

- Patient education, anaesthesia regimen and surgical protocol, early mobilisation, and multimodal pain control

- Mean LoS 3.0 days

- Usual care pathway not reported

90 days

 Teeny et al. 2005 [43]

United States

TKR

Short-stay: 55

Usual care: 55

Short-stay: 69

Usual care: 71

Mean [range]

Short-stay: 70 [42–86]

Usual care: 69 [41–84]

- Mean LoS 4.4 days

- Intravenous fluids discontinued 1-day postop, catheters in place for a maximum of 24 h, early mobilisation

- Mean LoS 5.7 days

- Intravenous fluids discontinued 2 days postop, catheters in place for up to 48 h, mobilisation the day after surgery

3 months

 Yanik et al. 2018 [44]

United States

THR (30)

TKR (70)

Short-stay: 78

Usual care: 174

Short-stay: 10

Usual care: 10

Short-stay: 66 (9)

Usual care: 66 (9)

- Mean LoS 1.7 days

- Patient education, spinal anaesthesia without femoral nerve blocks, multimodal pain techniques, and early mobilisation

- Mean LoS 3.2 days

- Usual care pathway not reported

90 days

Other observational study designs

 Castorina et al. 2017 [52]

Retrospective observational study

Italy

TKR

Short-stay: 95

Usual care: 37

Not reported

Short-stay: 71 (7)

Usual care: 74 (6)

- LoS not reported

- No tourniquet used, tranexamic acid used at 3-time points, no articular drainage

- LoS not reported

- Regular articular drainage was used, tranexamic acid was only used at two time points

2 months

 Edelmann et al. 2022 [73]

 Retrospective observational study

Switzerland

THR (62)

TKR (38)

Short-stay: 302

Usual care: 138

Short-stay THR: 51

Usual care THR: 42

Short-stay and usual care TKR: 64

Short-stay THR: 61 (11)

Usual care THR: 67 (11)

Short-stay TKR: 64 (11)

Usual care TKR: 67 (9)

- Mean LoS TKR 6.0 days

- Mean LoS THR 5.3 days

- Preoperative education and counselling, preoperative physiotherapy, local anaesthetic for infiltration and nerve blocks, perioperative oral analgesia, early mobilisation, continuous audit and improvement

- Mean LoS TKR 8.4 days

- Mean LoS THR 7.7 days

- No patient education, no preoperative physiotherapy, no local anaesthetic, no oral analgesia, no early mobilisation, no continuous improvement and audit

90 days

 Jiang et al. 2022 [46]

Non-randomised prospective controlled study

China

TKR

Short-stay: 106

Usual care: 142

Short-stay: 55

Usual care: 59

Short-stay: 74 (6)

Usual care: 75 (6)

- Mean LoS 9.6 days

- Preoperative, intraoperative, and postoperative interventions with a focus on patient education, preoperative analgesia, and fasting guidelines

- Mean LoS 11.3 days

- General anaesthetic, no multimodal analgesia, no blood protocol, mobilisation 1-day post-surgery

5 days

 Liao et al. 2022 [47]

Non-randomised controlled study (retrospective allocation to control and intervention groups

China

TKR

Short-stay: 40

Usual care: 40

Short-stay: 60

Usual care: 55

Short-stay: 65 (5)

Usual care: 65 (5)

- Length of stay not reported

- General anaesthetic, operation room temperature adjusted to a lower temperature, all fluids headed to a specific temperature, body temperature monitored, thermal mattress used

- LoS not reported

- No special heat preservation method was adopted during the surgery

3 months

 Reinhard et al. 2023 [68]

Retrospective matched pair analysis

Germany

THR

Short-stay: 315

Usual care: 315

Short-stay: 43

Usual care: 43

Short-stay: 65 [20]

Usual care: 65 [20]

- Length of stay not reported

- Local infiltration analgesia, patient education, gain training, tranexamic acid, local infiltration analgesia, early mobilisation

- Length of stay not reported

- No gait training or analgesic medication before surgery, long-lasting spinal anaesthesia, no tranexamic acid, drains applied

24 h

 Ripolles-Melchor et al. 2019 [72]

Non-randomised prospective controlled study (allocated to control and intervention groups based on hospital)

Spain

THR (37)

TKR (63)

Short-stay: 1592

Usual care: 4554

Short-stay: 58

Usual care: 58

Short-stay: 70 [63–76]

Usual care: 71 [64–76]

- Median LoS 4 days

- Sixteen Enhanced Recovery After Surgery Components based on Soffin & YaDeau’s recommendations

- Mean LoS 5 days

- Usual care pathway not defined; individual patients were allocated to intervention or control groups based on the hospital’s short-stay protocols

30 days

 Scott et al. 2012 [36]

Consecutive snapshot audits from all 22 orthopaedic units in Scotland

Scotland

THR (52)

TKR (48)

Short-stay: 405

Usual care: 873

Not reported

Short-stay: 68 (11)

Usual care: 68 (10)

- Median LoS 4 days

- Optimisation of pre-existing conditions, patient education, non-opioid multimodal analgesia, early mobilisation, and functional discharge

- Median LoS 5 days

- Usual care pathway not reported

12 weeks

 Slim et al. 2022 [51]

Non-randomised matched groups (retrospective allocation to control and intervention groups)

France

THR

TKR

Short-stay: 21,081

Usual care: 21,081

Not reported

Not reported

- LoS not reported

- Short-stay pathway not described, but episodes of short-stay care were coded for inclusion in the study

- LoS not reported

- Usual care pathway not reported

90 days

 Wang et al. 2023 [48]

China

THR

Short-stay: 45

Usual care: 45

Short-stay: 71

Usual care: 56

Short-stay: 66 (9)

Usual care: 74 (12)

- Mean LoS 14 days

- Preoperative optimisation, patient education, preoperative nutrition, multimodal pain relief, controlling body temperature, and early mobilisation

- Mean LoS 16 days

- No protocol for pre-operative management

3 days

  1. IQR interquartile range, LoS length of stay, SD standard deviation, THR total hip replacement, TKR total knee replacement