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Table 1 Baseline characteristics according to alcohol consumption habit

From: Risk of newly developed atrial fibrillation by alcohol consumption differs according to genetic predisposition to alcohol metabolism: a large-scale cohort study with UK Biobank

 

Non-drinkers (n = 114,528)

Mild-to-moderate drinkers (n = 207,254)

Heavy drinkers (n = 77,547)

P-value

Demographic data

 Age, years

57.0±8.2

56.9±8.0

56.4±79

<0.001

 Sex, %

36,978 (32.3)

83,621 (40.3)

61,382 (79.2)

<0.001

 BMI, kg/m2

28.2±5.5

26.7±4.4

27.8±4.2

<0.001

Past medical history, %

 Hypertension

32,398 (28.3)

48,433 (23.4)

24,048 (31.0)

<0.001

 Diabetes mellitus

7014 (6.1)

5998 (2.9)

3336 (4.0)

<0.001

 Myocardial infarction

6993 (6.1)

9237 (4.5)

5139 (6.6)

<0.001

 Dyslipidemia

14,528 (12.7)

21,954 (10.6)

1168 (14.4)

<0.001

 Chronic kidney disease

6791 (5.9)

7182 (3.5)

2722 (3.5)

<0.001

 Heart failure

4528 (4.0)

5134 (2.5)

2888 (3.7)

<0.001

 Stroke

2689 (2.3)

3823 (1.8)

1943 (2.5)

<0.001

Physical examination

 SBP, mmHg

137.0±18.8

137.4±18.5

142.8±18.0

<0.001

 DBP, mmHg

81.3±10.1

81.8±9.9

85.3±10.0

<0.001

Smoking, %

   

<0.001

 Never smoker

69,351 (60.8)

120,481 (58.3)

28,467 (37.0)

 

 Ex-smoker

32,184 (28.2)

71,657 (34.7)

35,468 (46.1)

 

 Current smoker

12,514 (11.0)

14,508 (7.0)

13,056 (17.0)

 

PRS for alcohol use

0.011±0.021

0.012±0.020

0.013±0.019

<0.001

  1. BMI Body mass index, PRS Polygenic risk score, S(D)BP Systolic (diastolic) blood pressure