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Fig. 2 | BMC Medicine

Fig. 2

From: Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still’s disease

Fig. 2

Cell-surface markers of monocyte subsets in patients with AOSD. A MFI (median fluorescence intensity) of CD80, CD86, HLA-DR, and CD163 for three monocyte subsets. B MFI of CD80, CD86, HLA-DR, and CD163 on total monocytes from AOSD patients and HCs. C MFI of CD80, CD86, HLA-DR, and CD163 on IMs from AOSD patients and HCs. D Immunofluorescence images and detection of phagocytic activity of CMs and IMs. E The proportion of Th1, Th17, and Treg cells after coculture of CD4 + T cells with CMs or IMs. F The concentrations of IL-1β, IL-6, TNF, CCL8, and CXCL10 in the cell supernatants of CMs and IMs. The results show the means ± SD. * = p < 0.05, ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001, ns = not significance, by ANOVA test followed by Tukey’s test for multiple comparisons in A, E, and F or by Mann–Whitney U test in B and C

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BMC Medicine

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