Skip to main content

Table 2 Baseline medical characteristics, including presence of high-risk conditionsa

From: Substantial health and economic burden of COVID-19 during the year after acute illness among US adults at high risk of severe COVID-19

Characteristic, n (%)

All Patients (N = 19,558)

Age Group, years

Disposition During Acute COVID-19 Illness

18–64 (n = 9381)

 ≥ 65 (n = 10,177)

No Hospitalization (n = 15,457)

Hospitalization Without ICU Admission (n = 2916)

ICU Admission (n = 1185)

High-risk condition

 Aged ≥ 65 years

10,177 (52.0)

0 (0.0)

10,177 (100)

7187 (46.5)

2157 (74.0)

833 (70.3)

 Cancer history

2933 (15.0)

722 (7.7)

2211 (21.7)

2214 (14.3)

533 (18.3)

186 (15.7)

 Chronic kidney disease

2783 (14.2)

612 (6.5)

2171 (21.3)

1646 (10.7)

832 (28.5)

305 (25.7)

 Chronic liver diseaseb

218 (1.1)

88 (0.9)

130 (1.3)

139 (0.9)

56 (1.9)

23 (1.9)

 Chronic lung diseasec

2566 (13.1)

915 (9.8)

1651 (16.2)

1755 (11.4)

613 (21.0)

198 (16.7)

 Dementia or other neurologic condition

1121 (5.7)

237 (2.5)

884 (8.7)

716 (4.6)

320 (11.0)

85 (7.2)

 Diabetes

6081 (31.1)

2060 (22.0)

4021 (39.5)

4168 (27.0)

1319 (45.2)

594 (50.1)

 Down syndrome

4 (0.02)

4 (0.04)

0 (0.0)

2 (0.01)

1 (0.03)

1 (0.1)

 Heart conditiond

6347 (32.5)

1593 (17.0)

4754 (46.7)

4375 (28.3)

1472 (50.5)

500 (42.2)

 HIV

158 (0.8)

107 (1.1)

51 (0.5)

120 (0.8)

28 (1.0)

10 (0.8)

 Hypertension

11,823 (60.5)

3966 (42.3)

7857 (77.2)

8558 (55.4)

2323 (79.7)

942 (79.5)

 Immunocompromised statee

13,931 (71.2)

6464 (68.9)

7467 (73.4)

10,848 (70.2)

2222 (76.2)

861 (72.7)

 Mental health conditionf

3214 (16.4)

1615 (17.2)

1599 (15.7)

2453 (15.9)

570 (19.6)

191 (16.1)

 Overweight or obesity

7361 (37.6)

3742 (39.9)

3619 (35.6)

5615 (36.3)

1209 (41.5)

537 (45.3)

 Pregnancy or recent pregnancyg

375 (1.9)

375 (4.0)

0 (0.0)

331 (2.1)

41 (1.4)

3 (0.3)

 Sickle cell disease or thalassemia

72 (0.4)

45 (0.5)

27 (0.3)

57 (0.4)

12 (0.4)

3 (0.3)

 Smoking, current or previous

3463 (17.7)

1274 (13.6)

2189 (21.5)

2393 (15.5)

806 (27.6)

264 (22.3)

 Solid organ or blood stem cell transplanth

34 (0.2)

22 (0.2)

12 (0.1)

21 (0.1)

12 (0.4)

1 (0.1)

 Stroke or cerebrovascular disease

1730 (8.9)

326 (3.5)

1404 (13.8)

1152 (7.5)

440 (15.1)

138 (11.7)

 Substance use disorderi

589 (3.0)

317 (3.4)

272 (2.7)

413 (2.7)

145 (5.0)

31 (2.6)

 Tuberculosis

124 (0.6)

68 (0.7)

56 (0.6)

97 (0.6)

22 (0.8)

5 (0.4)

Number of high-risk conditions, mutually exclusive

 1

3623 (18.5)

3147 (33.6)

476 (4.7)

3322 (21.5)

205 (7.0)

96 (8.1)

 2

3229 (16.5)

2376 (25.3)

853 (8.4)

2878 (18.6)

235 (8.1)

116 (9.8)

 3

2999 (15.3)

1590 (17.0)

1409 (13.8)

2496 (16.2)

340 (11.7)

163 (13.8)

 4

2626 (13.4)

936 (10.0)

1690 (16.6)

2087 (13.5)

383 (13.1)

156 (13.2)

 5

2377 (12.2)

573 (6.1)

1804 (17.7)

1729 (11.2)

442 (15.2)

206 (17.4)

 6

1880 (9.6)

356 (3.8)

1524 (15.0)

1293 (8.4)

413 (14.2)

174 (14.7)

 7

1327 (6.8)

207 (2.2)

1120 (11.0)

835 (5.4)

370 (12.7)

122 (10.3)

 ≥ 8

1497 (7.7)

196 (2.1)

1301 (12.8)

817 (5.3)

528 (18.1)

152 (12.8)

Care setting of COVID-19 diagnosis

 Inpatient

3385 (17.3)

847 (9.0)

2538 (24.9)

0 (0.0)

2431 (83.4)

954 (80.5)

 Outpatient

16,173 (82.7)

8534 (91.0)

7639 (75.1)

15,457 (100)

485 (16.6)

231 (19.5)

Disposition during acute COVID-19 illness

 No hospitalization

15,457 (79.0)

8270 (88.2)

7187 (70.6)

   

 Hospitalization without ICU admission

2916 (14.9)

759 (8.1)

2157 (21.2)

   

 ICU admission

1185 (6.1)

352 (3.8)

833 (8.2)

   

 COVID-19 inpatient stay that overlaps acute and post-acute phases; > 30 days

143 (0.7)

35 (0.4)

108 (1.1)

0 (0.0)

36 (1.2)

107 (9.0)

  1. ICU intensive care unit
  2. aConditions placing individuals at high risk of developing severe illness from COVID-19 were determined by the Centers for Disease Control and Prevention [29]
  3. bIncludes cirrhosis, nonalcoholic fatty liver disease, alcoholic liver disease, and autoimmune hepatitis
  4. cIncludes moderate to severe asthma, bronchiectasis, bronchopulmonary dysplasia, chronic obstructive pulmonary disease, emphysema, chronic bronchitis, interstitial lung disease, pulmonary fibrosis, cystic fibrosis, pulmonary embolism, and pulmonary hypertension
  5. dIncludes heart failure, coronary artery disease, and cardiomyopathies
  6. eIncluded both primary immunocompromised state (genetic condition) and secondary or acquired immunocompromised state (prolonged use of medication that weakens the immune system, such as corticosteroids or antimetabolites). Qualifying diagnoses included HIV/AIDS, solid malignancy, bone marrow transplant, organ transplant, rheumatologic/inflammatory conditions, primary immunodeficiency, chronic kidney disease or end-stage renal disease, and hematologic malignancy
  7. fIncluded mood disorder or schizophrenia spectrum disorder
  8. gRecent pregnancy defined as a pregnancy occurring within 42 days before the index date; excludes women aged ≥ 45 years
  9. hIncluding bone marrow transplant
  10. iIncluded alcohol, opioid, or cocaine abuse
Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us