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Table 5 Medications with frequency increases ≥ 10% from baseline to post-acute phasea by disposition during acute COVID-19

From: Substantial health and economic burden of COVID-19 during the year after acute illness among US adults at high risk of severe COVID-19

USC Medication Class Description

No Hospitalization (n = 15,457)

Hospitalization Without ICU Admission (n = 2916)

ICU Admission (n = 1185)

Baseline Phase, n (%)

Post-Acute Phase, n (%)

Change From Baseline to Post-Acute Phase, Δ (% Change)

Baseline Phase, n (%)

Post-Acute Phase, n (%)

Change From Baseline to Post-Acute Phase, Δ (% Change)

Baseline Phase, n (%)

Post-Acute Phase, n (%)

Change From Baseline to Post-Acute Phase, Δ (% Change)

Vitamins

619 (4.0)

891 (5.8)

272 (43.9)

100 (3.4)

166 (5.7)

66 (66.0)

52 (4.4)

80 (6.8)

28 (53.8)

Miscellaneous preparations

603 (3.9)

792 (5.1)

189 (31.3)

161 (5.5)

250 (8.6)

89 (55.3)

67 (5.7)

105 (8.9)

38 (56.7)

Blood factors

499 (3.2)

627 (4.1)

128 (25.7)

134 (4.6)

185 (6.3)

51 (38.1)

42 (3.5)

76 (6.4)

34 (81.0)

Hemostatic modifiers

1366 (8.8)

1618 (10.5)

252 (18.4)

533 (18.3)

765 (26.2)

232 (43.5)

194 (16.4)

336 (28.4)

142 (73.2)

Nutrients and supplements

625 (4.0)

771 (5.0)

146 (23.4)

258 (8.8)

325 (11.1)

67 (26.0)

97 (8.2)

150 (12.7)

53 (54.6)

Cardiac agents

808 (5.2)

968 (6.3)

160 (19.8)

279 (9.6)

352 (12.1)

73 (26.2)

116 (9.8)

165 (13.9)

49 (42.2)

Antineoplastic targeted therapy

384 (2.5)

454 (2.9)

70 (18.2)

109 (3.7)

135 (4.6)

26 (23.9)

43 (3.6)

55 (4.6)

12 (27.9)

Thyroid therapy

1722 (11.1)

1958 (12.7)

236 (13.7)

361 (12.4)

427 (14.6)

66 (18.3)

139 (11.7)

168 (14.2)

29 (20.9)

Neurologic/neuromuscular disorders

2736 (17.7)

3065 (19.8)

329 (12.0)

749 (25.7)

836 (28.7)

87 (11.6)

305 (25.7)

370 (31.2)

65 (21.3)

Gastrointestinal

3769 (24.4)

4097 (26.5)

328 (8.7)

879 (30.1)

1015 (34.8)

136 (15.5)

354 (29.9)

483 (40.8)

129 (36.4)

Psychotherapeutic drugs

4697 (30.4)

5077 (32.8)

380 (8.1)

871 (29.9)

1043 (35.8)

172 (19.7)

308 (26.0)

410 (34.6)

102 (33.1)

Diagnostic aids

2394 (15.5)

2614 (16.9)

220 (9.2)

611 (21.0)

710 (24.3)

99 (16.2)

283 (23.9)

328 (27.7)

45 (15.9)

  1. ICU intensive care unit, USC Uniform System of Classification
  2. aThe baseline period was the 12 months before the index date, and the post-acute phase spanned from 1 to 13 months after the index date