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Table 9 Medical costs during baseline and post-acute phasesa stratified by disposition during acute COVID-19b

From: Substantial health and economic burden of COVID-19 during the year after acute illness among US adults at high risk of severe COVID-19

Cost Description

No Hospitalization (n = 15,457)

Hospitalization Without ICU Admission (n = 2916)

ICU Admission (n = 1185)

Baseline Phase

Post-Acute Phase

Change From Baseline to Post-Acute Phase, Δ (% Change)

Baseline Phase

Post-Acute Phase

Change From Baseline to Post-Acute Phase, Δ (% Change)

Baseline Phase

Post-Acute Phase

Change From Baseline to Post-Acute Phase, Δ (% Change)

Inpatient visits

 Total cost

55,006,160

71,173,890

16,167,729 (29.4)

37,551,499

48,817,949

11,266,450 (30.0)

7,752,746

28,486,963

20,734,217 (267.4)

 Standard costs, patient n

1528

1526

 

808

886

 

187

465

 

  Mean ± SD

35,999 ± 45,790

46,641 ± 57,520

10,642 (29.6)

46,475 ± 66,096

55,099 ± 71,721

8625 (18.6)

41,459 ± 40,551

61,262 ± 86,428

19,804 (47.8)

  Median (Q1; Q3)

21,462 (14,504; 38,044)

29,627 (14,953; 54,520)

8164 (38.0)

27,718 (16,260; 52,083)

31,155 (13,937; 70,003)

3437 (12.4)

27,769 (15,380; 52,190)

28,301 (6212; 78,651)

532 (1.9)

 Nonzero costs, patient n

1527

1520

–7 (–0.5)

805

877

72 (8.9)

187

460

273 (146.0)

  Mean ± SD

36,022 ± 45,795

46,825 ± 57,559

10,803 (30.0)

46,648 ± 66,158

55,665 ± 71,869

9017 (19.3)

41,459 ± 40,551

61,928 ± 86,659

20,470 (49.4)

  Median (Q1; Q3)

21,480 (14,508; 38,079)

29,780 (15,003; 54,950)

8300 (38.6)

27,784 (16,312; 52,229)

31,884 (14,314; 70,217)

4100 (14.8)

27,769 (15,380; 52,190)

29,569 (7503; 79,361)

1800 (6.5)

Readmission

 Total cost

7,197,035

16,934,054

9,737,019 (135.3)

6,826,276

19,945,967

13,119,691 (192.2)

1,484,911

19,715,081

18,230,170 (1227.7)

 Standard costs, patient n

165

348

 

130

477

 

32

320

 

  Mean ± SD

43,618 ± 44,151

48,661 ± 63,658

5043 (11.6)

52,510 ± 70,981

41,815 ± 65,602

–10,694 (–20.4)

46,403 ± 34,640

61,610 ± 87,131

15,206 (32.8)

  Median (Q1; Q3)

26,212 (14,990; 60,310)

24,379 (15,647; 56,754)

–1834 (–7.0)

29,916 (17,377; 53,143)

19,431 (4351; 51,298)

–10,485 (–35.0)

31,421 (21,650; 67,656)

28,680 (2796; 86,050)

–2740 (–8.7)

 Nonzero costs, patient n

165

346

181 (109.7)

130

463

333 (256.2)

32

315

283 (884.4)

  Mean ± SD

43,618 ± 44,151

48,942 ± 63,734

5324 (12.2)

52,510 ± 70,981

43,080 ± 66,177

–9430 (–18.0)

46,403 ± 34,640

62,588 ± 87,472

16,184 (34.9)

  Median (Q1; Q3)

26,212 (14,990; 60,310)

24,660 (15,783; 57,039)

–1552 (–5.9)

29,916 (17,377; 53,143)

20,524 (5966; 52,693)

–9392 (–31.4)

31,421 (21,650; 67,656)

29,724 (3262; 86,370)

–1697 (–5.4)

Outpatient visits

 Total cost

165,229,755

182,955,168

17,725,413 (10.7)

62,832,431

80,468,457

17,636,026 (28.1)

24,675,886

29,818,339

5,142,453 (20.8)

 Standard costs, patient n

15,362

15,183

 

2882

2878

 

1169

1162

 

  Mean ± SD

10,756 ± 26,701

12,050 ± 32,084

1294 (12.0)

21,802 ± 94,115

27,960 ± 93,624

6158 (28.2)

21,109 ± 100,596

25,661 ± 83,776

4553 (21.6)

  Median (Q1; Q3)

4226 (1642; 10,315)

4598 (1763; 11,469)

372 (8.8)

6584 (2552; 17,830)

9307 (3257; 23,704)

2723 (41.4)

5090 (1719; 14,685)

9539 (4143; 21,553)

4449 (87.4)

 Nonzero costs, patient n

15,361

15,183

–178 (–1.2)

2882

2877

–5 (–0.2)

1169

1162

–7 (–0.6)

  Mean ± SD

10,756 ± 26,702

12,050 ± 32,084

1294 (12.0)

21,802 ± 94,115

27,970 ± 93,639

6168 (28.3)

21,109 ± 100,596

25,661 ± 83,776

4553 (21.6)

  Median (Q1; Q3)

4227 (1642; 10,315)

4598 (1763; 11,469)

371 (8.8)

6584 (2552; 17,830)

9313 (3257; 23,704)

2729 (41.4)

5090 (1719; 14,685)

9539 (4143; 21,553)

4449 (87.4)

Emergency department visits

 Total cost

14,492,784

11,234,026

–3,258,759 (–22.5)

4,705,450

4,066,393

–639,057 (–13.6)

1,520,211

1,476,150

–44,060 (–2.9)

 Standard costs, patient n

4368

3427

 

1168

968

 

407

361

 

  Mean ± SD

3318 ± 4780

3278 ± 5038

–40 (–1.2)

4029 ± 6268

4201 ± 5832

172 (4.3)

3735 ± 4241

4089 ± 12,625

354 (9.5)

  Median (Q1; Q3)

2245 (1304; 3755)

2250 (1293; 3723)

4 (0.2)

2569 (1567; 4738)

2676 (1609; 4931)

107 (4.1)

2445 (1486; 4518)

2467 (1418; 4128)

21 (0.9)

 Nonzero costs, patient n

4361

3423

–938 (–21.5)

1168

968

–200 (–17.1)

406

361

–45 (–11.1)

  Mean ± SD

3323 ± 4782

3282 ± 5039

–41 (–1.2)

4029 ± 6268

4201 ± 5832

172 (4.3)

3744 ± 4242

4089 ± 12,625

345 (9.2)

  Median (Q1; Q3)

2249 (1304; 3761)

2254 (1293; 3725)

5 (0.2)

2569 (1567; 4738)

2676 (1609; 4931)

107 (4.1)

2454 (1488; 4518)

2467 (1418; 4128)

12 (0.5)

Prescription claims

 Total cost

53,453,402

58,721,207

5,267,806 (9.9)

14,012,113

17,079,036

3,066,923 (21.9)

5,915,746

7,091,044

1,175,298 (19.9)

 Standard costs, patient n

14,144

14,069

 

2604

2644

 

1097

1111

 

  Mean ± SD

3779 ± 15,333

4174 ± 16,026

395 (10.4)

5381 ± 13,865

6460 ± 15,983

1079 (20.0)

5393 ± 14,846

6383 ± 17,463

990 (18.4)

  Median (Q1; Q3)

556 (162; 2340)

577 (166; 2799)

21 (3.8)

1362 (346; 5153)

1818 (445; 6091)

456 (33.5)

1096 (297; 4402)

1700 (406; 5822)

604 (55.1)

 Nonzero costs, patient n

14,144

14,069

–75 (–0.5)

2604

2644

40 (1.5)

1097

1111

14 (1.3)

  Mean ± SD

3779 ± 15,333

4174 ± 16,026

395 (10.4)

5381 ± 13,865

6460 ± 15,983

1079 (20.0)

5393 ± 14,846

6383 ± 17,463

990 (18.4)

  Median (Q1; Q3)

556 (162; 2340)

577 (166; 2799)

21 (3.8)

1362 (346; 5153)

1818 (445; 6091)

456 (33.5)

1096 (297; 4402)

1700 (406; 5822)

604 (55.1)

All medical costs (outpatient, inpatient, and prescription claims)

 Total cost

273,689,317

312,850,265

39,160,948 (14.3)

114,396,043

146,365,442

31,969,399 (28.0)

38,344,378

65,396,345

27,051,967 (70.6)

 Standard costs, patient n

15,416

15,313

 

2899

2890

 

1177

1172

 

  Mean ± SD

17,754 ± 40,000

20,430 ± 47,834

2677 (15.1)

39,461 ± 108,454

50,645 ± 113,091

11,185 (28.3)

32,578 ± 106,772

55,799 ± 113,215

23,221 (71.3)

  Median (Q1; Q3)

6196 (2343; 16,739)

6717 (2497; 18,298)

521 (8.4)

13,543 (4388; 40,384)

16,906 (5460; 51,456)

3363 (24.8)

8493 (2978; 27,941)

18,578 (6643; 57,224)

10,085 (118.7)

 Nonzero costs, patient n

15,416

15,313

–103 (–0.7)

2899

2889

–10 (–0.3)

1177

1171

–6 (–0.5)

  Mean ± SD

17,754 ± 40,000

20,430 ± 47,834

2677 (15.1)

39,461 ± 108,454

50,645 ± 113,091

11,185 (28.3)

32,578 ± 106,772

55,799 ± 113,215

23,221 (71.3)

  Median (Q1; Q3)

6196 (2343; 16,739)

6717 (2497; 18,298)

521 (8.4)

13,543 (4388; 40,384)

16,906 (5460; 51,456)

3363 (24.8)

8493 (2978; 27,941)

18,578 (6643; 57,224)

10,085 (118.7)

  1. Standard cost patient n’s (used to calculate standard mean and median) reflect the number of patients who had any healthcare encounter for the specified outcome (eg, all patients with ≥ 1 outpatient visit during the specified time frame). Nonzero cost patient n’s (used to calculate nonzero mean and median) reflect the number of patients who had any costs associated with the specified outcome (eg, all patients with costs > 0 attributable to outpatient visits)
  2. COVID-19 coronavirus disease 2019, ICU intensive care unit
  3. aThe baseline phase was the 12 months before the index date, and the post-acute phase spanned from 1 to 13 months after the index date
  4. bAll costs are in US dollars rounded to the nearest dollar