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Table 2 Associations between current night shift work and the risk of incident COPD (n = 277,059)

From: Associations between long-term night shift work and incidence of chronic obstructive pulmonary disease: a prospective cohort study of 277,059 UK Biobank participants

Variables

HR (95% CI) by current work schedule

P for trend

Day workers

Shift, but rarely/some night shifts

Usual/permanent night shifts

Case/all subjects

4984/229,478

1177/37,057

397/10,524

 

Model 1

1 [reference]

1.48 (1.38, 1.57)

1.75 (1.58, 1.94)

 < 0.001

Model 2

1 [reference]

1.60 (1.50, 1.70)

2.02 (1.82, 2.24)

 < 0.001

Model 3

1 [reference]

1.29 (1.21, 1.37)

1.47 (1.32, 1.63)

 < 0.001

Model 4

1 [reference]

1.28 (1.20, 1.37)

1.49 (1.35, 1.66)

 < 0.001

  1. Abbreviations: COPD Chronic obstructive pulmonary disease, BMI Body mass index, IPAQ International Physical Activity Questionnaire
  2. Model 1: Unadjusted
  3. Model 2: Model 1 + age and sex
  4. Model 3: Model 2 + ethnicity, BMI, Townsend deprivation index, sleep duration, smoking status, alcohol drinking, IPAQ activity group, and chronotype
  5. Model 4: Model 3 + asthma