Intervention group (n = 95) | Control group (n = 97) | |
---|---|---|
Age, median month (IQR) | 33.0 (16.0–47.0) | 33.0 (16.5–44.0) |
Shanghai residency | 30 (31.6) | 27 (27.8) |
Gender, male (%) | 36 (37.9) | 49 (50.5) |
CHD subtypes, n (%) | ||
PDA | 31 (32.6) | 32 (33.0) |
PS | 12 (12.6) | 14 (14.4) |
VSD | 33 (34.7) | 32 (33.0) |
ASD | 19 (20.0) | 19 (19.6) |
Motor developmental quotient, median (IQR) | ||
GMQ | 91.0 (85.0–94.0) | 91.0 (85.0–97.0) |
FMQ | 94.0 (91.0–100.0) | 97.0 (91.0–100.0) |
TMQ | 92.0 (86.0–96.0) | 92.0 (89.0–97.5) |
Modified Ross score, n (%) | ||
0 | 37 (38.9) | 39 (40.2) |
1 | 45 (47.4) | 44 (45.4) |
2 | 13 (13.7) | 14 (14.4) |
Cardiac structural indexes, median (IQR) | ||
LVDd, mm | 33.3 (29.2–36.3) | 32.6 (29.4–36.1) |
Z score of LVDd | 0.16 (− 0.63–1.42) | 0.14 (− 0.50–1.21) |
LVDs, mm | 21.2 (18.7–23.1) | 20.8 (18.6–23.3) |
Z score of LVDs | 0.46 (− 0.31–1.36) | 0.38 (− 0.27–1.34) |
LVPWd, mm | 4.6 (4.0–5.1) | 4.4 (3.7–5.0) |
Z score of LVPWd | 0.36 (− 0.20–0.99) | 0.16 (− 0.46–0.77) |
LVPWs, mm | 7.6 (7.0–9.0) | 7.3 (6.4–8.5) |
Z score of LVPWs | − 0.27 (− 1.11–0.54) | − 0.58 (− 1.45–0.20) |
LVEF, % | 69.0 (64.5–71.0) | 66.0 (63.5–70.0) |
MPA, % | 1.2 (1.0–1.4) | 1.2 (1.0–1.4) |
MV, m/s | 1.0 (1.0–1.2) | 1.0 (1.0–1.2) |
TV, m/s | 0.8 (0.8–1.0) | 0.8 (0.8–1.0) |
Z score of LVPWs | − 0.27 (− 1.11–0.54) | − 0.58 (− 1.45–0.20) |
Bone quality, median (IQR) | ||
SOS, m/s | 3445.0 (3233.0–3543.5) | 3382.0 (3261.0–3516.0) |
Bone strength percentile | 55.0 (31.0–78.0) | 44.0 (20.0–76.5) |
Z score of SOS | 0.1 (− 0.5–0.8) | − 0.2 (− 0.85–0.75) |
SAS score, median (IQR) | ||
Rude score | 30.0 (26.5–37.0) | 33.0 (27.0–39.0) |
Standard score | 37.5 (33.1–46.3) | 41.3 (33.8–48.8) |
ZCBS score, median (IQR) | 22.0 (14.5–30.0) | 22.5 (14.3–30.0) |
SF-36 score, median (IQR) | ||
PCS | 339.0 (304.0–369.0) | 348.0 (288.0–370.0) |
MCS | 308.0 (242.5–340.0) | 277.0 (237.5–327.0) |
Total score | 640.0 (552.5–706.5) | 629.0 (532.5–686.0) |
Physical development indicators, median (IQR) | ||
Weight, kg | 14.0 (10.0–17.0) | 13.5 (9.6–16.7) |
Height, cm | 93.0 (79.0–104.0) | 92.5 (78.0–100.0) |
BMI, kg/m2 | 16.3 (15.4–17.7) | 16.1 (15.0–17.3) |
Upper-arm circumference, cm | 16.0 (15.0–17.0) | 16.0 (14.9–17.0) |
Head circumference, cm | 48.3 (45.0–50.0) | 47.7 (46.0–49.5) |
Chest circumference, cm | 50.5 (47.0–53.5) | 50.0 (47.0–54.0) |