Intervention group (n = 95) | Control group (n = 97) | |||
---|---|---|---|---|
Median (IQR) | p value | Median (IQR) | p value | |
SOS (m/s) | ||||
Baseline | 3445.0 (3233.0–3543.5) | - | 3373.3 (3240.0–3516.0) | - |
1 month | 3407.0 (3269.0–3523.5) | 0.969 | 3386.0 (3247.0–3529.5) | 0.601 |
3 months | 3438.0 (3265.0–3528.0) | 0.614 | 3410.0 (3240.0–3544.0) | 0.083 |
6 months | 3407.0 (3264.5–3545.0) | 0.239 | 3425.0 (3287.0–3545.0) | 0.001* |
Bone mineral density (BMD) percentiles | ||||
Baseline | 55.0 (31.0–78.0) | - | 41.0 (19.5–75.0) | - |
1 month | 58.0 (24.0–85.0) | 0.957 | 47.0 (18.0–81.5) | 0.868 |
3 months | 54.0 (22.5–78.5) | 0.350 | 47.0 (17.5–83.0) | 0.615 |
6 months | 50.0 (27.5–77.0) | 0.343 | 49.0 (26.0–83.0) | 0.261 |
Z score of SOS | ||||
Baseline | 0.1 (− 0.5–0.8) | - | − 0.2 (− 0.9–0.7) | - |
1 month | 0.2 (− 0.7–1.0) | 0.809 | − 0.2 (− 0.9–0.9) | 0.733 |
3 months | 0.1 (− 0.8–0.8) | 0.700 | − 0.1 (− 1.0–1.0) | 0.767 |
6 months | 0.0 (− 0.6–0.8) | 0.291 | 0.0 (− 0.6–1.0) | 0.367 |
Upper-arm circumference, cm | ||||
Baseline | 16.0 (15.0–17.0) | - | 16.0 (15.0–17.0) | - |
1 month | 16.0 (15.0–17.0) | 0.026 | 15.5 (15.0–17.0) | 0.544 |
3 months | 16.0 (15.0–18.0) | < 0.001 | 16.0 (15.0–17.0) | 0.029 |
6 months | 17.0 (15.0–18.0) | < 0.001 | 16.0 (15.0–18.0) | < 0.001* |
BMI, kg/m2 | ||||
Baseline | 16.3 (15.4–17.7) | - | 16.1 (14.9–17.3) | - |
1 month | 16.5 (15.3–17.8) | 0.561 | 16.1 (15.0–17.3) | 0.526 |
3 months | 16.1 (15.0–17.7) | 0.494 | 16.1 (14.8–17.5) | 0.964 |
6 months | 16.3 (15.6–17.2) | 0.938 | 15.6 (14.7–17.1) | 0.036 |
Chest circumference, cm | ||||
Baseline | 50.5 (47.0–53.5) | - | 50.0 (47.0–53.9) | - |
1 month | 51.0 (47.0–54.5) | 0.001 | 51.0 (47.0–53.9) | 0.346 |
3 months | 51.5 (47.5–54.0) | < 0.001 | 52.0 (47.0–54.0) | 0.032 |
6 months | 52.0 (49.0–55.0) | < 0.001 | 52.0 (49.0–54.0) | < 0.001* |
Head circumference, cm | ||||
Baseline | 48.3 (45.0–50.0) | - | 47.7 (46.0–49.5) | - |
1 month | 48.0 (45.5–49.5) | 0.109 | 47.8 (45.1–49.5) | 0.923 |
3 months | 48.5 (46.0–5.0) | < 0.001 | 48.5 (46.0–50.0) | 0.003* |
6 months | 49.0 (47.0–50.0) | < 0.001 | 49.0 (46.6–50.0) | < 0.001* |
Height, cm | ||||
Baseline | 93.0 (79.0–104.0) | - | 92.0 (77.3–100.4) | - |
1 month | 94.8 (81.0–107.0) | < 0.001 | 94.3 (79.3–101.9) | < 0.001* |
3 months | 97.0 (82.0–108.0) | < 0.001 | 95.8 (81.3–104.0) | < 0.001* |
6 months | 98.5 (81.0–109.0) | < 0.001 | 98.0 (84.4–107.9) | < 0.001* |
Weight, kg | ||||
Baseline | 14.0 (10.0–17.0) | - | 13.5 (9.6–16.7) | - |
1 month | 14.6 (10.2–17.5) | < 0.001 | 13.4 (10.0–16.8) | 0.005* |
3 months | 14.7 (11.2–18.1) | < 0.001 | 14.3 (10.7–17.2) | < 0.001* |
6 months | 15.0 (11.6–19.2) | < 0.001 | 15.0 (11.2–18.2) | < 0.001* |